Chronic hepatitis B and liver schistosomiasis: a deleterious association

Background Chronic hepatitis B (CHB) and schistosomiasis are prevalent in several countries, but the impact of this association is unknown. We aimed to investigate the prevalence and morbidity of this co-infection in Minas Gerais, an endemic area of schistosomiasis in Brazil. Methods In total, 406 a...

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Bibliographic Details
Published in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2014-03, Vol.108 (3), p.159-164
Main Authors: Andrade, J. R., Silva, Luciana Diniz, Guimarães, Camila Mendes, Bassetti-Soares, Eric, Cambraia, Rodrigo Dias, Couto, O. F. M., Teixeira, Rosângela
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Biological and medical sciences
Brazil - epidemiology
Comorbidity
Cross-Sectional Studies
Diseases caused by trematodes
Female
General aspects
Helminthic diseases
Hepatitis B, Chronic - epidemiology
Human viral diseases
Humans
Infectious diseases
Liver - parasitology
Liver Cirrhosis - epidemiology
Liver Cirrhosis - etiology
Male
Medical sciences
Middle Aged
Multivariate Analysis
Parasitic diseases
Prevalence
Schistosomiases
Schistosomiasis mansoni - epidemiology
Sex Distribution
Viral diseases
Viral hepatitis
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Summary:Background Chronic hepatitis B (CHB) and schistosomiasis are prevalent in several countries, but the impact of this association is unknown. We aimed to investigate the prevalence and morbidity of this co-infection in Minas Gerais, an endemic area of schistosomiasis in Brazil. Methods In total, 406 adults with CHB (HBsAg positive >6 months) were included in a cross-sectional study. CHB was classified as replicative (HBV DNA ≥2.000 IU/ml), and low replicative or inactive hepatitis B carriers (HBV DNA
ISSN:0035-9203
1878-3503
DOI:10.1093/trstmh/tru010