Examining emotional modulation of pain and spinal nociception in Native Americans: A preliminary investigation

• Published in: International journal of psychophysiology 2013-11, Vol.90 (2), p.272-281
• Main Authors: Palit, Shreela, Kerr, Kara L., Kuhn, Bethany L., DelVentura, Jennifer L., Terry, Ellen L., Bartley, Emily J., Shadlow, Joanna O., Rhudy, Jamie L.
• Format: Article
• Language: English
• Subjects: Adult; Ankle; Arousal - physiology; Behavioral psychophysiology; Biological and medical sciences; Electric Stimulation; Electromyogram; Emotion; Emotions - physiology; Ethnic differences; European Continental Ancestry Group; Female; Fundamental and applied biological sciences. Psychology; Galvanic Skin Response; Humans; Indians, North American - psychology; Male; Middle Aged; Nociception - physiology; Pain; Pain - ethnology; Pain - psychology; Pain Measurement; Pain modulation; Pain Threshold; Photic Stimulation; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Reflex - physiology; RIII reflex; Spinal Cord - physiopathology
• ISSN: 0167-8760; 1872-7697
• DOI: 10.1016/j.ijpsycho.2013.08.009

Pain problems are more prevalent in Native Americans than in any other group in the U.S., and this might result from group differences in pain modulation. This study was designed to examine emotional modulation of pain and spinal nociception in healthy, pain-free Native Americans (n=21) relative to non-Hispanic Whites (n=20). To assess emotional modulation of pain and the nociceptive flexion reflex (NFR, a physiological measure of spinal nociception), participants underwent a well-validated emotional picture-viewing paradigm during which suprathreshold pain stimuli were delivered to the ankle. Compared to Whites, Native Americans reported less pleasure to erotic pictures and failed to show corrugator reactivity to mutilation pictures. Unlike Whites, Native Americans only evidenced pain inhibition in response to erotica, but no pain facilitation (disinhibition) to mutilation pictures. Emotional modulation of NFR was similar in both groups. These preliminary findings suggest that Native Americans failed to disinhibit pain, perhaps due to over-activation of pain inhibitory mechanisms. Chronic over-activation of this system could ultimately exhaust it, thus putting Native Americans at future risk for chronic pain. •Native Americans (NA) and Whites differed in emotional modulation of pain.•Whites showed pain inhibition and pain disinhibition (facilitation).•NAs showed pain inhibition but not pain disinhibition (facilitation).•NAs and Whites did not differ in emotional modulation of spinal nociception.•Over-activation of supraspinal pain inhibition might deplete this resource in NAs.