Three cerebrosides from the sea cucumber Cucumaria frondosa

To study the chemical constituents of the sea cucumber Cucumaria frondosa. Three sphingosine-type glucocerebrosides, CF-3-1, CF-3-2 and CF-3-3 were isolated by means of high performance liquid chromatography (HPLC) from a cerebroside molecular species 3 which was obtained from the less polar fractio...

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Bibliographic Details
Published in:Chinese journal of natural medicines 2012-03, Vol.10 (2), p.105-109
Main Authors: LA, Ming-Ping, SHAO, Jun-Jie, JIAO, Jian, YI, Yang-Hua
Format: Article
Language:English
Subjects:
Cerebrosides
chemical composition
Cucumaria frondosa
ethanol
Glycosphingolipids
high performance liquid chromatography
Holothurioidea
Holothuroidea
Marine
Sea Cucumber
spectroscopy
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Summary:To study the chemical constituents of the sea cucumber Cucumaria frondosa. Three sphingosine-type glucocerebrosides, CF-3-1, CF-3-2 and CF-3-3 were isolated by means of high performance liquid chromatography (HPLC) from a cerebroside molecular species 3 which was obtained from the less polar fraction of the 65% EtOH extract of the sea cucumber Cucumaria frondosa Gunnerus. The structures of these cerebrosides were determined on the basis of chemical and spectroscopic evidences. Three compounds were isolated from the sea cucumber Cucumaria frondosa for the first time. CF-3-3 and CF-3-2 were obtained as pure compounds for the first time.
ISSN:1875-5364
1875-5364
DOI:10.3724/SP.J.1009.2012.00105