The principles and feasibility of disease eradication

Smallpox eradication framed disease eradication as a monumental public health achievement in global health equity. The principles of disease eradication are encapsulated in a constellation of four conditions: biologic feasibility, adequate public health infrastructure, sufficient funding, and sustai...

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Bibliographic Details
Published in:Vaccine 2011-12, Vol.29 (S4), p.D70-D73
Main Authors: Dowdle, Walter R, Cochi, Stephen L
Format: Article
Language:English
Subjects:
Allergy and Immunology
Biological & chemical terrorism
Communicable Disease Control - economics
Communicable Disease Control - methods
Communicable Disease Control - organization & administration
Conflicts of interest
Disease
Disease control
Disease Eradication - economics
Disease Eradication - methods
Disease Eradication - organization & administration
Dracunculiasis - epidemiology
Dracunculiasis - prevention & control
Dracunculus medinensis
Eradication
funding
Geography
Global
Global Health
Humans
infrastructure
Initiatives
Measles - epidemiology
Measles - prevention & control
National security
opportunity costs
Poliomyelitis
Poliomyelitis - epidemiology
Poliomyelitis - prevention & control
politics
Principles
prioritization
Public health
Rubella - epidemiology
Rubella - prevention & control
Tropical diseases
Vaccines
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Summary:Smallpox eradication framed disease eradication as a monumental public health achievement in global health equity. The principles of disease eradication are encapsulated in a constellation of four conditions: biologic feasibility, adequate public health infrastructure, sufficient funding, and sustained political/societal will. Where the constellation exists, national eradication occurs in the absence of a global initiative. Assessing the feasibility of global eradication requires determining the constellation gaps for nations of all regions and identifying the human and financial resources to fill the gaps. The economic and humanitarian benefits of eradication have strong appeal. Global polio and guinea worm efforts are underway. Regional eradication of measles and rubella has been achieved in the Americas and other diseases have been proposed. Global decisions on disease eradication should include careful consideration of opportunity costs and prioritization of limited global health resources, with the objective of providing the most appropriate, cost-beneficial, and equitable outcome of disease control.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.04.006