Hoigne syndrome following an intravenous injection of ceftriaxone: a case report

Hoigne's syndrome is characterized by the development of acute clinical manifestations which are mainly psycho-sensorial. Classically, these features immediately follow the injection of procaine penicillin G. We report a 59-year-old man who presented with psycho-organic manifestations that occu...

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Bibliographic Details
Published in:La revue de medecine interne 2014-03, Vol.35 (3), p.199-201
Main Authors: Landais, A, Marty, N, Bessis, D, Pages, M, Blard, J-M
Format: Article
Language:fre
Subjects:
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - adverse effects
Brain Abscess - drug therapy
Ceftriaxone - administration & dosage
Ceftriaxone - adverse effects
Drug Hypersensitivity - diagnosis
Humans
Injections, Intravenous
Male
Middle Aged
Syndrome
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Summary:Hoigne's syndrome is characterized by the development of acute clinical manifestations which are mainly psycho-sensorial. Classically, these features immediately follow the injection of procaine penicillin G. We report a 59-year-old man who presented with psycho-organic manifestations that occurred just after the intravenous injection of ceftriaxone; to our knowledge, this is the first case of Hoigne's syndrome reported after an injection of this antibiotic. The pathophysiologic basis of this syndrome is still unknown. It is important to keep in mind its clinical characteristics, which may mimic immuno-allergic symptoms. It should be differentiated from anaphylactic manifestations because Hoigne's syndrome allows the continuation of the treatment.
ISSN:1768-3122
DOI:10.1016/j.revmed.2013.02.027