Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

Changes in the conformation of a peptide anchored onto the external surface of mesoporous silica nanoparticles have been used to design novel temperature-controlled delivery systems.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2014-01, Vol.50 (24), p.3184-3186
Main Authors: de la Torre, Cristina, Agostini, Alessandro, Mondragón, Laura, Orzáez, Mar, Sancenón, Félix, Martínez-Máñez, Ramón, Marcos, María D, Amorós, Pedro, Pérez-Payá, Enríque
Format: Article
Language:English
Subjects:
Models, Molecular
Nanoparticles - chemistry
Particle Size
Peptides - chemistry
Porosity
Protein Structure, Secondary
Silicon Dioxide - chemistry
Surface Properties
Temperature
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Description
Summary:Changes in the conformation of a peptide anchored onto the external surface of mesoporous silica nanoparticles have been used to design novel temperature-controlled delivery systems.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc49421g