Functional long-term results after rectal cancer surgery—technique of the athermal mesorectal excision

• Published in: International journal of colorectal disease 2014-03, Vol.29 (3), p.285-292
• Main Authors: Touloumtzidis, Aristotelis, Sostmann, Björn, Hilgers, Nicole, Renter, Marc A., Kühn, Petra, Goretzki, Peter E., Lammers, Bernhard J.
• Format: Article
• Language: English
• Subjects: Adenocarcinoma - pathology; Adenocarcinoma - surgery; Adult; Aged; Aged, 80 and over; Autonomic Pathways - injuries; Chemoradiotherapy, Adjuvant; Colorectal cancer; Dissection - adverse effects; Dissection - methods; Fasciotomy; Female; Follow-Up Studies; Gastroenterology; Health aspects; Hepatology; Humans; Internal Medicine; Male; Medicine; Medicine & Public Health; Methods; Middle Aged; Neoadjuvant Therapy; Original Article; Pelvis - innervation; Proctology; Rectal Neoplasms - pathology; Rectal Neoplasms - surgery; Rectum - surgery; Retrospective Studies; Sexual disorders; Sexual Dysfunction, Physiological - etiology; Surgery; Survival Rate; Urination Disorders - etiology
• ISSN: 0179-1958; 1432-1262
• DOI: 10.1007/s00384-013-1805-7

Purpose The total mesorectal excision (TME), embedded in a multimodal therapeutic concept, is accepted as the standard therapy of the advanced adenocarcinoma of the middle and lower thirds. The thermal damages of the autonomous nerves in the little pelvis caused by dissection devices remains a large problem. For our patients, we use water-jet dissection (WJD)-aided TME with the intention to minimise the rate of bladder and sexual function disorders. Methods From October 2001 until June 2010, we recorded 125 patients with an adenocarcinoma of the middle and lower third of the rectum. Ninety deep anterior rectum resections and 35 abdominoperineal rectum extirpations by WJD were performed. Of the patients, 27.2 % received neoadjuvant radiochemotherapy. Bladder and sexual function disorders were assessed by International Prostate Symptom Score and International Index of Erectile Function. Results The median follow-up period was 46 (2–117) months. Considering a local recurrence rate of 9.6 %, the tumour-specific 5-year survival of the entire collective was 75.4 %. Long-term bladder function disorders showed in 6.0 % (4/64) and sexual function disorders in 25.0 % (9/36) of the male patients in the course of time. Conclusion The specific advantage of the WJD technique is not only the facilitated dissection between the mesorectal fascia and the surrounding nervous structures in the little pelvis but also a completely athermal TME. The rate of bladder and sexual function disorders is an excellent result compared to that of international centres. Due to the size of the patient collective and the retrospective character of the study, further studies are necessary to validate the presented results.