Characterization of a 42 degree C-specific heart shock protein of mammalian cells

HeLa cells synthesize a particular heat shock protein that is induced only by heat shock at 42 degree C, and not at 45 degree C or by other stresses that induce major heat shock proteins. The authors further characterized the 42 degree C-specific protein. This protein was induced in mouse FM 3A cell...

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Bibliographic Details
Published in:Biochemistry (Easton) 1988-01, Vol.103 (1), p.81-85
Main Authors: Honda, K-I, Hatayama, T, Yukioka, M
Format: Article
Language:English
Subjects:
heat shock
mammalian cells
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Summary:HeLa cells synthesize a particular heat shock protein that is induced only by heat shock at 42 degree C, and not at 45 degree C or by other stresses that induce major heat shock proteins. The authors further characterized the 42 degree C-specific protein. This protein was induced in mouse FM 3A cells as well as in human HeLa cells. In both cell lines, the protein was resolved into two spots, a basic polypeptide and an acidc one. The results suggested that the 42 degree C-specific protein may have some function in the cytoplasm of mammalian cells during mild heat shock.
ISSN:0006-2960