Uric Acid Levels in Obstructive Sleep Apnea Patients with Atrial Fibrillation

Background and Aims The objective of this observational study was to determine whether there is an association between atrial fibrillation (AF) and uric acid and to identify the risk markers for AF in obstructive sleep apnea (OSA). Methods Consecutive patients with newly diagnosed OSA were screened...

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Bibliographic Details
Published in:Archives of medical research 2014-02, Vol.45 (2), p.132-137
Main Authors: Wan, Yu-feng, Zheng, Yu-long, Niu, Hong-yan, Xu, Chuan-qin, He, Yuan-qiang, Wang, Yi, Chen, Jian-hui, Zheng, Dong-hui
Format: Article
Language:English
Subjects:
Adult
Aged
Atrial Fibrillation - blood
Atrial Fibrillation - complications
Atrial Fibrillation - physiopathology
Female
Humans
Internal Medicine
Logistic Models
Male
Middle Aged
Multivariate Analysis
Risk Factors
Sleep Apnea, Obstructive - blood
Sleep Apnea, Obstructive - complications
Uric Acid - blood
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Summary:Background and Aims The objective of this observational study was to determine whether there is an association between atrial fibrillation (AF) and uric acid and to identify the risk markers for AF in obstructive sleep apnea (OSA). Methods Consecutive patients with newly diagnosed OSA were screened at baseline. The final study population consisted of 516 patients. One hundred and eight patients had AF. Demographic, clinical, laboratory, and echocardiographic characteristics were carefully recorded. Logistic regression was used for the multivariate analysis of independent risk factors. Results Uric acid, triglyceride, high-density lipoprotein, C-reactive protein (CRP), left atrial diameter, interventricular septum thickness, apnea hypopnea index, and Epworth sleepiness scale were significantly higher in OSA patients with AF than in those without AF ( p
ISSN:0188-4409
1873-5487
DOI:10.1016/j.arcmed.2013.11.006