Ovarian Tissue Collection for Cryopreservation in Pediatric Age: Laparoscopic Technical Tips

Abstract As the number of young girls subjected to chemo and radiotherapy is steadily increasing it is our duty to try to preserve their future fertility and ovarian function. A possibility is to collect ovarian samples, cryopreserve them and reimplant the tissue when the treatments are over. We rep...

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Bibliographic Details
Published in:Journal of pediatric & adolescent gynecology 2014-04, Vol.27 (2), p.95-97
Main Authors: Lima, Mario, PhD, Gargano, Tommaso, MD, Fabbri, Raffaella, MD, Maffi, Michela, MD, Destro, Francesca, MD
Format: Article
Language:English
Subjects:
Adolescent
Child
Cryopreservation
Female
Fertility Preservation
Humans
Laparoscopy
Laparoscopy - methods
Neoplasms - drug therapy
Neoplasms - radiotherapy
Obstetrics and Gynecology
Ovarian cryopreservation
Ovary
Patient Positioning
Pediatrics
Tissue and Organ Harvesting - methods
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Summary:Abstract As the number of young girls subjected to chemo and radiotherapy is steadily increasing it is our duty to try to preserve their future fertility and ovarian function. A possibility is to collect ovarian samples, cryopreserve them and reimplant the tissue when the treatments are over. We report our 11 year experience with the use of laparoscopy to collect ovarian tissue samples. In particular we focus on the details of the surgical technique. The procedure was performed in 54 patients affected by malignancies or pathologies requiring chemo or radiotherapy, with good results. Cryopreservation seems to be a good option to preserve future fertility although it is still an experimental method.
ISSN:1083-3188
1873-4332
DOI:10.1016/j.jpag.2013.11.002