Terpenoid biotransformations by Mucor species

Terpenoids are natural products of great interest due to their widespread use in agrochemicals, drugs, fragrances, flavouring and pigments. Biocatalysts are increasingly being used in the search for new derivatives with improved properties especially to obtain structurally novel leads for new drugs...

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Bibliographic Details
Published in:Phytochemistry reviews 2013-12, Vol.12 (4), p.857-876
Main Authors: Oliveira Silva, Eliane de, Furtado, Niege Araçari Jacometti Cardoso, Aleu, Josefina, Collado, Isidro González
Format: Article
Language:English
Subjects:
Agrochemicals
Biocatalysts
Biochemistry
Biomedical and Life Sciences
Biotransformation
Catalysts
Chemistry/Food Science
Drugs
Fragrances
Life Sciences
Mucor
Natural products
Organic chemicals
Organic Chemistry
Pharmacology
Pigments
Plant Genetics and Genomics
Plant Sciences
Terpenes
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Summary:Terpenoids are natural products of great interest due to their widespread use in agrochemicals, drugs, fragrances, flavouring and pigments. Biocatalysts are increasingly being used in the search for new derivatives with improved properties especially to obtain structurally novel leads for new drugs which are difficult to obtain using conventional organic chemical methods. This review, covering up to the end of 2012, reports on the application of Mucor species as catalysts in terpenoid biotransformation to obtain new drug targets, enhance pharmacological activity or decrease the unwanted effects of starting material.
ISSN:1568-7767
1572-980X
DOI:10.1007/s11101-013-9313-5