8-Nitro-cGMPaA New Player in Antibacterial Autophagy

In this issue of Molecular Cell, Ito et al. (2013) identify 8-nitro-cGMP as a new autophagy inducer mediating the clearance of invading bacteria in a mechanism that depends on protein S-guanylation and Lys63-linked ubiquitination. This study reveals an additional link between the innate immune respo...

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Bibliographic Details
Published in:Molecular cell 2013-12, Vol.52 (6), p.767-768
Main Authors: Rawet-Slobodkin, Moran, Elazar, Zvulun
Format: Article
Language:English
Online Access:Get full text
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Summary:In this issue of Molecular Cell, Ito et al. (2013) identify 8-nitro-cGMP as a new autophagy inducer mediating the clearance of invading bacteria in a mechanism that depends on protein S-guanylation and Lys63-linked ubiquitination. This study reveals an additional link between the innate immune response and autophagy.
ISSN:1097-2765
DOI:10.1016/j.molcel.2013.12.006