Small diameter tubular structure design using solvent-free textile techniques

• Published in: Journal of applied polymer science 2014-04, Vol.131 (8), p.np-n/a
• Main Authors: Chrzanowska, Olga, Struszczyk, Marcin Henryk, Krucinska, Izabella
• Format: Article
• Language: English
• Subjects: Applied sciences; Biological and medical sciences; biomaterials; biomedical applications; Design engineering; differential scanning calorimetry (DSC); Exact sciences and technology; Fibers and threads; Forms of application and semi-finished materials; Materials science; Medical sciences; Polymer industry, paints, wood; Polymers; spectroscopy; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology of polymers; Technology. Biomaterials. Equipments
• ISSN: 0021-8995; 1097-4628
• DOI: 10.1002/app.40147

ABSTRACT The aim of research was to elaborate the non‐biodegradable (made of polypropylene (PP)) and resorbable (made of polylactide (PLA)) tubular fibrous structures for the reconstruction of the vascular vessels. For the mentioned structures design, nonconventional manufacturing techniques such as melt blown, melt electrospinning, and melt electroblowing were used. Three techniques were chosen as methods allowing on the fibrous structures manufacture containing fibers in nano‐ or submicro‐size diameter. Other advantages of free‐solvent technique use is the reduction in the clinical adverse events associated with solvent resided in the fibrous structure during the fabrication. The tubular fibrous structures of PP and PLA using above‐mentioned techniques were designed. In first stage, the analysis of the processing parameters influence on the nonbiodegradable and biodegradable tubular structures fiber diameter was performed. Subsequently, the validation step was the analysis of the influence of processing parameters on PP and PLA structural properties for each manufacturing techniques was investigated. The research results confirmed the ability of the tubular structures manufacture with various fiber diameter depending on the applied technique and processing parameters. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40147.