Human health risk from organ-specific accumulation of toxic metals and response of antioxidants in edible fish species from Chenab River, Pakistan

• Published in: Environmental science and pollution research international 2014-03, Vol.21 (6), p.4409-4417
• Main Authors: Waheed, Sidra, Kamal, Atif, Malik, Riffat Naseem
• Format: Article
• Language: English
• Subjects: Acids; Animals; antioxidant activity; Antioxidants; Aquatic organisms; Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Bioaccumulation; Biomarkers; Cadmium; catalase; Catalase - metabolism; Chromium; Cobalt; Comparative analysis; Copper; Diet - statistics & numerical data; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Exposure - analysis; Environmental Exposure - statistics & numerical data; Environmental Health; Fish; Fishes - metabolism; Food chains; Food contamination & poisoning; Food Contamination - analysis; Food Contamination - statistics & numerical data; Gills; Glutathione; Glutathione - metabolism; Guaiacol; Health risk assessment; Health risks; Heavy metals; human health; Humans; iron; Laboratories; Lead; Lipids; Liver; Liver - metabolism; Metals; Metals - metabolism; Metals - toxicity; Muscles; Muscles - metabolism; nickel; Oxidative stress; Pakistan; peroxidase; Peroxidase - metabolism; Pollutants; Pollution studies; Regression analysis; Research Article; risk; Risk Assessment; Rivers; Rivers - chemistry; Seafood; Superoxide dismutase; Superoxide Dismutase - metabolism; toxicity; Trophic levels; trophic relationships; Waste Water Technology; Water Management; Water Pollutants, Chemical - metabolism; Water Pollutants, Chemical - toxicity; Water pollution; Water Pollution Control; Water Pollution, Chemical - statistics & numerical data; zinc
• ISSN: 0944-1344; 1614-7499
• DOI: 10.1007/s11356-013-2385-3

In the current study, the bioaccumulation of essential and nonessential metals and related antioxidant activity were analyzed in three organs (muscle, gills, and liver) of herbivorous (HF) and carnivorous (CF) edible fish of Chenab River. The comparative analysis revealed a more heterogeneous accumulation of metals in the muscles of HF fish than that of CF fish [chromium (Cr, 3.4 μg g⁻¹), cobalt (Co, 1.7 μg g⁻¹), copper (Cu, 3 μg g⁻¹), and iron (Fe, 45 μg g⁻¹) versus Cr (1.3 μg g⁻¹), Co (0.1 μg g⁻¹), Cu (1.1 μg g⁻¹), and Fe (33 μg g⁻¹), respectively, P