Midterm oncological outcome and clinicopathological characteristics of anterior prostate cancers treated by endoscopic extraperitoneal radical prostatectomy

Purpose The purpose of the study is to characterise the clinicopathological characteristics of anterior prostate cancer (APC) compared to posterior prostate cancer (PPC)s and to determine the midterm oncological outcomes of patients with APCs undergoing endoscopic extraperitoneal radical prostatecto...

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Bibliographic Details
Published in:World journal of urology 2014-04, Vol.32 (2), p.393-398
Main Authors: Good, Daniel W., Stewart, Grant D., Zakikhani, Paimaun, Yuen, Henry, Riddick, Antony C. P., Bollina, Prasad R., O’Donnell, Marie, Stolzenburg, Jens-Uwe, McNeill, S. Alan
Format: Article
Language:English
Subjects:
Aged
Cohort Studies
Disease-Free Survival
Humans
Kallikreins - blood
Kaplan-Meier Estimate
Laparoscopy
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Recurrence, Local
Nephrology
Oncology
Original Article
Prostate - pathology
Prostate - surgery
Prostate-Specific Antigen - blood
Prostatectomy
Prostatic Neoplasms - blood
Prostatic Neoplasms - pathology
Prostatic Neoplasms - surgery
Retrospective Studies
Treatment Outcome
Urology
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Summary:Purpose The purpose of the study is to characterise the clinicopathological characteristics of anterior prostate cancer (APC) compared to posterior prostate cancer (PPC)s and to determine the midterm oncological outcomes of patients with APCs undergoing endoscopic extraperitoneal radical prostatectomy (EERPE). Methods A retrospective review was carried out on all EERPEs performed in 2009. Pathology reports (transrectal ultrasound biopsy and surgical specimen), specimen photographs, demographic details and oncological outcome data from a prospectively maintained database were reviewed. Unpaired t test, chi-squared test and Kaplan–Meier curves were used for the analysis. Results Of 139 patients identified, 53 were APCs (38 %) and 86 were PPCs (62 %). Significantly, greater number of repeat biopsies were required to diagnose APCs ( p  = 0.02) and they had significantly fewer positive biopsy cores ( p  = 0.0005). The APC group had a significantly higher PSA density (PSAd) with (
ISSN:0724-4983
1433-8726
DOI:10.1007/s00345-013-1114-3