Incidence of first heart failure hospitalisation and mortality in Aboriginal and non-Aboriginal patients in Western Australia, 2000–2009

• Published in: International journal of cardiology 2014-04, Vol.173 (1), p.110-117
• Main Authors: Teng, Tiew-Hwa Katherine, Katzenellenbogen, Judith M, Thompson, Sandra C, Sanfilippo, Frank M, Knuiman, Matthew, Geelhoed, Elizabeth, Hobbs, Michael, Bessarab, Dawn, Hung, Joseph
• Format: Article
• Language: English
• Subjects: Aboriginal; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Cardiology. Vascular system; Cardiovascular; Cohort Studies; Cross-Sectional Studies; Female; Heart; Heart failure; Heart Failure - diagnosis; Heart Failure - economics; Heart Failure - ethnology; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Hospitalization - economics; Humans; Incidence; Indigenous; Male; Medical sciences; Middle Aged; Population Surveillance - methods; Risk factors; Socioeconomic Factors; Survival; Western Australia - ethnology; Young Adult
• ISSN: 0167-5273; 1874-1754; 1874-1754
• DOI: 10.1016/j.ijcard.2014.02.020

Abstract Objectives To compare the incidence of first heart failure (HF) hospitalisation, antecedent risk factors and 1-year mortality between Aboriginal and non-Aboriginal populations in Western Australia (2000–2009). Methods A population-based cohort aged 20–84 years comprising Aboriginal (n = 1013; mean 54 ± 14 years) and non-Aboriginal patients (n = 16,366; mean 71 ± 11 years) with first HF hospitalisation was evaluated. Age and sex-specific incidence rates and HF antecedents were compared between subpopulations. Regression models were used to examine 30-day and 1-year (in 30-day survivors) mortality. Results Aboriginal patients were younger, more likely to reside in rural/remote areas (76% vs 23%) and to be women (50.6% vs 41.7%, all p < 0.001). Aboriginal (versus non-Aboriginal) HF incidence rates were 11-fold higher in men and 23-fold in women aged 20–39 years, declining to about 2-fold in patients aged 70–84 years. Ischaemic and rheumatic heart diseases were more common antecedents of HF in younger (< 55 years) Aboriginal versus non-Aboriginal patients (p < 0.001). Hypertension, diabetes, chronic kidney disease, renal failure, chronic obstructive pulmonary disease, and a high Charlson comorbidity index (>= 3) were also more prevalent in younger and older Aboriginal patients (p < 0.001). Although 30-day mortality was similar in both subpopulations, Aboriginal patients aged < 55 years had a 1.9 risk-adjusted hazard ratio (HR) for 1-year mortality (p = 0.015). Conclusions Aboriginal people had substantially higher age and sex-specific HF incidence rate and prevalence of HF antecedents than their non-Aboriginal counterparts. HR for 1-year mortality was also significantly worse at younger ages, highlighting the urgent need for enhanced primary and secondary prevention of HF in this population.