Differences in the risk factors of reflux esophagitis according to age in Korea

Summary The prevalence of gastroesophageal reflux disease in Korea has been believed to be low, but the incidence of gastroesophageal reflux disease in Korea is expected to increase because of the longer life expectancy and more ingestion of westernized food. The aim of this study was to report diff...

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Bibliographic Details
Published in:Diseases of the esophagus 2014-02, Vol.27 (2), p.116-121
Main Authors: Park, C. H., Kim, K. O., Baek, I. H., Choi, M. H., Jang, H. J., Kae, S. H., Kim, J. B., Baik, G. H., Shin, W. G., Kim, K. H., Kim, H. Y.
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Case-Control Studies
Coffee
Cohort Studies
Drinking Behavior
Esophagitis, Peptic - diagnosis
Esophagitis, Peptic - epidemiology
Female
gastroesophageal reflux disease
Helicobacter Infections - epidemiology
Helicobacter pylori
Hernia, Hiatal - epidemiology
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Overweight - epidemiology
Prospective Studies
reflux esophagitis
Republic of Korea - epidemiology
risk factor
Risk Factors
Sex Factors
Smoking - epidemiology
Young Adult
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Summary:Summary The prevalence of gastroesophageal reflux disease in Korea has been believed to be low, but the incidence of gastroesophageal reflux disease in Korea is expected to increase because of the longer life expectancy and more ingestion of westernized food. The aim of this study was to report differences in the risk factors of reflux esophagitis (RE) according to age in Korea. We prospectively recruited the subjects who had RE among those who visited a health promotion center for upper gastrointestinal cancer surveillance at Hallym Medical Center (five institutions) between January 2008 and February 2009. The enrolled study participants comprised 742 subjects with RE and 1484 healthy controls. The independent risk factors of RE in young and adult group were male sex, smoking, coffee, body mass index ≥ 25, hiatal hernia, and Helicobacter pylori negativity. The risk factors of RE in elderly group were smoking, coffee, and hiatal hernia. The risk factors for RE according to age group were found to differ. In elderly group, Helicobacter pylori infection was not a significant protective factor contrary to young and adult groups.
ISSN:1120-8694
1442-2050
DOI:10.1111/j.1442-2050.2012.01417.x