Avian influenza vaccines against H5N1 ‘bird flu’

Highlights • We review the development and application of inactivated vaccines. • We review the development and application of recombinant virus vector vaccines. • Recombinant duck enteritis virus (DEV) vector vaccine shows superior efficacy in ducks and broilers. • A DNA vaccine is effective and cl...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 2014-03, Vol.32 (3), p.147-156
Main Authors: Li, Chengjun, Bu, Zhigao, Chen, Hualan
Format: Article
Language:English
Subjects:
avian influenza
Biological and medical sciences
Biotechnology
Biotechnology - trends
Birds
Fundamental and applied biological sciences. Psychology
H5N1
Humans
Immunization
Influenza A Virus, H5N1 Subtype - immunology
Influenza Vaccines - therapeutic use
Influenza, Human - prevention & control
Internal Medicine
Mass Vaccination
Poultry
vaccine
Vaccines
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Summary:Highlights • We review the development and application of inactivated vaccines. • We review the development and application of recombinant virus vector vaccines. • Recombinant duck enteritis virus (DEV) vector vaccine shows superior efficacy in ducks and broilers. • A DNA vaccine is effective and close to being used for H5N1 avian influenza (AI).
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2014.01.001