Esophageal actinomycosis in a patient with end‐stage renal disease

Actinomycosis of esophagus is uncommon. Herpes simplex virus, cytomegalovirus, candidiasis, tuberculosis, and other fungal infections are the commonly reported infections in both immunocompromised and immunocompetent patients. We report a case of esophageal actinomycosis in an end‐stage renal diseas...

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Bibliographic Details
Published in:Hemodialysis international 2014-04, Vol.18 (2), p.544-546
Main Authors: Nagaraju, Shankar Prasad, Kirpalani, Dilip Ashok, Bhabhe, Aditya S., Prasad, Raghvendra, Shah, Hardik, Kirpalani, Ashok L.
Format: Article
Language:English
Subjects:
Actinomyces - isolation & purification
Actinomycosis - etiology
Actinomycosis - pathology
Adult
end‐stage renal disease
Esophageal actinomycosis
Esophageal Diseases - microbiology
Female
Humans
immunocompromised state
Kidney Failure, Chronic - microbiology
Kidney Failure, Chronic - therapy
Renal Dialysis
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Summary:Actinomycosis of esophagus is uncommon. Herpes simplex virus, cytomegalovirus, candidiasis, tuberculosis, and other fungal infections are the commonly reported infections in both immunocompromised and immunocompetent patients. We report a case of esophageal actinomycosis in an end‐stage renal disease patient. A 28‐year‐old lady, known case of systemic lupus erythematosus, hepatitis B virus infection with end‐stage renal disease on regular maintenance hemodialysis since 5 years presented with history of epigastric pain and odynophagia for 1 week. Her upper gastrointestinal endoscopic examination revealed extensive necrotic areas with membrane in the esophagus. Histopathology revealed actinomycotic colonies and bacterial clumps. She was treated with intravenous penicillin followed by oral ampicillin for 6 months. She showed marked clinical improvement, and repeat endoscopy showed healing of ulceration and no evidence of actinomycosis.
ISSN:1492-7535
1542-4758
DOI:10.1111/hdi.12124