Patterns of care and survival of glioblastoma patients: A comparative study between 2004 and 2008 in Lyon, France

The treatment of glioblastomas (GBMs) has changed significantly since 2005. However, the extent to which this change has improved overall survival (OS) of patients treated outside clinical trials remains to be determined. We compared the patterns of care and OS of all GBM patients diagnosed in 2004...

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Bibliographic Details
Published in:Revue neurologique 2014-03, Vol.170 (3), p.222-227
Main Authors: Badaoui, N., Meyronet, D., Cartalat-Carel, S., Guyotat, J., Jouanneau, E., d’Hombres, A., Sunyach, M.P., Jouvet, A., Louis-Tisserand, G., Archinet, A., Frappaz, D., Bauchet, L., Honnorat, J., Ducray, F.
Format: Article
Language:English
Subjects:
Aged
Angiogenesis Inhibitors - therapeutic use
Antibodies, Monoclonal, Humanized - therapeutic use
Antineoplastic Agents - therapeutic use
Bevacizumab
Biological and medical sciences
Brain Neoplasms - drug therapy
Brain Neoplasms - mortality
Brain Neoplasms - radiotherapy
Brain Neoplasms - therapy
Bévacizumab
Chemoradiotherapy
Chemotherapy, Adjuvant
Combined Modality Therapy
Cranial Irradiation
Dacarbazine - analogs & derivatives
Dacarbazine - therapeutic use
Disease Management
Epidemiology
Female
France - epidemiology
Glioblastoma
Glioblastoma - drug therapy
Glioblastoma - mortality
Glioblastoma - radiotherapy
Glioblastoma - therapy
Glioblastome
Humans
Kaplan-Meier Estimate
Male
Medical sciences
Middle Aged
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
Neoplasm Recurrence, Local - drug therapy
Neurology
Nitrosourea Compounds - therapeutic use
Palliative Care
Patterns of care
Temozolomide
Traitement
Treatment Outcome
Tumors
Tumors of the nervous system. Phacomatoses
Témozolomide
Épidemiologie
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Summary:The treatment of glioblastomas (GBMs) has changed significantly since 2005. However, the extent to which this change has improved overall survival (OS) of patients treated outside clinical trials remains to be determined. We compared the patterns of care and OS of all GBM patients diagnosed in 2004 (n=105) and in 2008 (n=130) in our center. Younger patients (aged
ISSN:0035-3787
DOI:10.1016/j.neurol.2013.09.007