An Integrated Microrobotic Platform for On-Demand, Targeted Therapeutic Interventions

The presented microrobotic platform combines together the advantages of self‐folding NIR light sensitive polymer bilayers, magnetic alginate microbeads, and a 3D manipulation system, to propose a solution for targeted, on‐demand drug and cell delivery. First feasibility studies are presented togethe...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2014-02, Vol.26 (6), p.952-957
Main Authors: Fusco, Stefano, Sakar, Mahmut Selman, Kennedy, Stephen, Peters, Christian, Bottani, Rocco, Starsich, Fabian, Mao, Angelo, Sotiriou, Georgios A., Pané, Salvador, Pratsinis, Sotiris E., Mooney, David, Nelson, Bradley J.
Format: Article
Language:English
Subjects:
alginate microbeads
Alginates
Animals
Cell Culture Techniques
Cell Proliferation
Cell Survival
Design engineering
Drug Delivery Systems - instrumentation
Drugs
Equipment Design
Feasibility Studies
Glucuronic Acid
Graphite
Hexuronic Acids
Hydrogels
Lasers
Magnetic Fields
Magnetite Nanoparticles
Mesenchymal Stromal Cells - physiology
Mice
Microorganisms
microrobotics
Microspheres
Microtechnology - instrumentation
Nanocomposites
Platforms
responsive hydrogels
Robotics - instrumentation
self-folding
targeted drug and cell delivery
Temperature
Three dimensional
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Summary:The presented microrobotic platform combines together the advantages of self‐folding NIR light sensitive polymer bilayers, magnetic alginate microbeads, and a 3D manipulation system, to propose a solution for targeted, on‐demand drug and cell delivery. First feasibility studies are presented together with the potential of the full design.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201304098