Serum Sickness-Like Reactions to Amoxicillin, Cefaclor, Cephalexin, and Trimethoprim-Sulfamethoxazole

The Food and Drug Administration's (EDA) spontaneous report system is the largest single source of data concerning adverse reactions to approved drugs in the United States. The authors examined this registry's spontaneously submitted reports of serum sickness-like reactions attributed to a...

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Bibliographic Details
Published in:The Journal of infectious diseases 1988-08, Vol.158 (2), p.474-477
Main Authors: Platt, Richard, Dreis, Michael W., Kennedy, Dianne L., Kuritsky, Joel N.
Format: Article
Language:English
Subjects:
Adverse drug reactions
Amoxicillin - adverse effects
Antibiotics
Biological and medical sciences
Cefaclor - adverse effects
Cephalexin - adverse effects
Cephalexin - analogs & derivatives
Concise Communications
Drug Combinations - adverse effects
Drug prescriptions
Drug toxicity and drugs side effects treatment
Food hypersensitivity
Health care administration
Humans
Marketing
Medical sciences
Medication administration
Miscellaneous (drug allergy, mutagens, teratogens...)
Pharmacology. Drug treatments
Physicians
Prescription drugs
Serum sickness
Serum Sickness - chemically induced
Sulfamethoxazole - adverse effects
Trimethoprim - adverse effects
Trimethoprim, Sulfamethoxazole Drug Combination
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Summary:The Food and Drug Administration's (EDA) spontaneous report system is the largest single source of data concerning adverse reactions to approved drugs in the United States. The authors examined this registry's spontaneously submitted reports of serum sickness-like reactions attributed to amoxicillin, cephalexin, cefaclor, or TMP-SMZ to determine whether the frequency of such reports differed for these compounds.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/158.2.474