Fear of Recurrence Impacts Health-Related Quality of Life and Continued Tobacco Use in Head and Neck Cancer Survivors

• Published in: Health psychology 2014-04, Vol.33 (4), p.373-381
• Main Authors: Van Liew, Julia R., Christensen, Alan J., Howren, M. Bryant, Hynds Karnell, Lucy, Funk, Gerry F.
• Format: Article
• Language: English
• Subjects: Addictive behaviors; Adult; Adult and adolescent clinical studies; Aged; Aged, 80 and over; Biological and medical sciences; Cross-Sectional Studies; Fear; Female; Head (Anatomy); Head and Neck Neoplasms - psychology; Health; Health Related Quality of Life; Human; Humans; Male; Medical sciences; Middle Aged; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Neck (Anatomy); Neoplasm Recurrence, Local - psychology; Neoplasms; Otorhinolaryngology (head neck, general aspects and miscellaneous); Otorhinolaryngology. Stomatology; Prospective Studies; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Quality of Life; Quality of Life - psychology; Regression Analysis; Relapse (Disorders); Survivors; Survivors - psychology; Survivors - statistics & numerical data; Tobacco Smoking; Tobacco Use - psychology; Tobacco, tobacco smoking; Toxicology; Tumors; Young Adult
• ISSN: 0278-6133; 1930-7810
• DOI: 10.1037/a0032680

Objective: To examine the impact of fear of recurrence (FOR) on health-related quality of life (HRQOL) and tobacco use among head and neck cancer (HNC) survivors. Methods: A cross-sectional subset of patients (N = 138) from a large, prospective study of oncologic outcomes in HNC was assessed for FOR, in addition to the parent study's ongoing assessments of HRQOL and tobacco use. FOR was measured using the Fear of Cancer Recurrence Inventory and HNC-specific HRQOL was assessed with the Head and Neck Cancer Inventory (HNCI). Tobacco use was patient-reported as "Current," "Previous," or "Never." Results: After controlling for relevant clinical and demographic variables, hierarchical regression analyses revealed that higher FOR significantly predicted lower HRQOL across all HNCI domains (eating (p < .05), aesthetics (p < .01), speech (p < .01), and social disruption (p = .001)) and increased tobacco use (p < .01). A total of 60.1% of the sample expressed clinically significant levels of FOR. These patients reported lower HRQOL (eating: p < .05, aesthetics: p < .05, social disruption: p < .05) and were more likely to be using tobacco compared with patients with subclinical FOR (26.6% and 4.9%, respectively; p < .01). Conclusions: Results suggest that FOR is prevalent among HNC survivors and is related to decreased HRQOL and increased tobacco use.