Primary bone marrow Hodgkin lymphoma in an HIV-negative patient

Classical Hodgkin lymphoma has distinct clinicopathological features and shows good response to treatment in most cases. Primary bone marrow-limited Hodgkin lymphoma is uncommon and primarily described in HIV-positive patients. It behaves as a distinct entity with aggressive clinical course and poor...

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Bibliographic Details
Published in:International journal of hematology 2014-04, Vol.99 (4), p.503-507
Main Authors: Dholaria, Bhagirathbhai, Alapat, Daisy, Arnaoutakis, Konstantinos
Format: Article
Language:English
Subjects:
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Biopsy
Bone Marrow - pathology
Bone Marrow Neoplasms - diagnosis
Bone Marrow Neoplasms - drug therapy
Case Report
Female
Hematologic and hematopoietic diseases
Hematology
HIV Seronegativity
Hodgkin Disease - diagnosis
Hodgkin Disease - drug therapy
Human viral diseases
Humans
Infectious diseases
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Medicine
Medicine & Public Health
Oncology
Positron-Emission Tomography
Reed-Sternberg Cells - pathology
Tomography, X-Ray Computed
Treatment Outcome
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Classical Hodgkin lymphoma has distinct clinicopathological features and shows good response to treatment in most cases. Primary bone marrow-limited Hodgkin lymphoma is uncommon and primarily described in HIV-positive patients. It behaves as a distinct entity with aggressive clinical course and poor response to available treatments. We discuss here a case of Hodgkin lymphoma with isolated involvement of bone marrow in an HIV-negative patient, which was successfully treated with conventional chemotherapy.
ISSN:0925-5710
1865-3774
DOI:10.1007/s12185-014-1532-z