Orofacial dermal fillers: foreign body reactions, histopathologic features, and spectrometric studies

Objective The aim of this study is to assess the different histopathologic presentations of dermal filler materials-induced foreign body reactions by spectrometric analyses. Study Design Sixteen cases of dermal filler foreign body reactions in the orofacial region were retrieved from the 2006-2013 p...

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Published in:Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2014-05, Vol.117 (5), p.617-625
Main Authors: Owosho, Adepitan A., BChD, Bilodeau, Elizabeth A., DMD, MD, MSEd, Vu, John, MD, PhD, Summersgill, Kurt F., DDS, PhD
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biocompatible Materials - adverse effects
Collagen - adverse effects
Cosmetic Techniques - adverse effects
Dentistry
Female
Foreign-Body Reaction - chemically induced
Foreign-Body Reaction - pathology
Humans
Male
Middle Aged
Photomicrography
Polymers - adverse effects
Spectrophotometry, Infrared
Surgery
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Summary:Objective The aim of this study is to assess the different histopathologic presentations of dermal filler materials-induced foreign body reactions by spectrometric analyses. Study Design Sixteen cases of dermal filler foreign body reactions in the orofacial region were retrieved from the 2006-2013 period. The histologic features were evaluated and categorized into 5 groups (I to V). Unstained deparaffinized sections of representative tissue from one case in each of groups I to IV were sent for spectrometric analysis, along with samples of 2 popular dermal fillers (Juvéderm and Radiesse). Results With the help of spectrometric analysis, we were able to correlate the histopathologic presentations with the specific type of dermal filler used.
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2014.01.018