Design and Mechanical Properties of a Novel Cerebral Flow Diverter Stent

Brain arterial aneurysms are localised dilatation in the wall of cerebral arteries that are common among adult population and associated with high incidence of morbidity and mortality. Using flow diverter stent alone to treat cerebral aneurysm is recognized as a safe and effective method. However, f...

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Bibliographic Details
Published in:Annals of biomedical engineering 2014-05, Vol.42 (5), p.960-970
Main Authors: Ma, Jiayao, You, Zhong, Byrne, James, Rizkallah, Rafik R.
Format: Article
Language:English
Subjects:
Alloys
Animals
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biomedical Engineering and Bioengineering
Biomedicine
Biophysics
Cerebrovascular Circulation
Classical Mechanics
Equipment Design
Finite Element Analysis
Intracranial Aneurysm - therapy
Porosity
Stents
Swine
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Summary:Brain arterial aneurysms are localised dilatation in the wall of cerebral arteries that are common among adult population and associated with high incidence of morbidity and mortality. Using flow diverter stent alone to treat cerebral aneurysm is recognized as a safe and effective method. However, flow diverter stents currently available have limitations due to their braided structures. In this paper a novel flow diverter stent is proposed. It is made out of nitinol tubes that provide adequate radial stiffness and tailored surface coverage to overcome problems of currently available braided stents while retaining low porosity and excellent longitudinal flexibility. Finite element analysis using Abaqus has been conducted to investigate radial stiffness, longitudinal flexibility, and maximum strain during packaging of a series of novel stent designs with varied geometric parameters. Results show that porosity below 70% can be achieved and provides radial stiffness and longitudinal flexibility comparable to those of the Neuroform stent that is commonly used for stent assisted coiling. The novel flow diverter has showed great potential for direct treatment of cerebral aneurysms.
ISSN:0090-6964
1573-9686
DOI:10.1007/s10439-013-0967-3