Limonoids from the leaves of Soymida febrifuga and their insect antifeedant activities

Three new phragmalin-type limonoids (1–3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. Three new phragmalin-type limonoids (1–3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. The structures of these compounds...

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 2014-02, Vol.24 (3), p.888-892
Main Authors: Yadav, P. Ashok, Suresh, G., Rao, M. Suri Appa, Shankaraiah, G., Usha Rani, P., Babu, K. Suresh
Format: Article
Language:English
Subjects:
Achaea janata
Animals
Antifeedant activity
Feeding Behavior - drug effects
Insecta - drug effects
Limonins - chemistry
Limonins - pharmacology
Limonoids
Meliaceae
Meliaceae - chemistry
Molecular Structure
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Leaves - chemistry
seco-Limonoids
Soymida febrifuga
Spodoptera litura
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Summary:Three new phragmalin-type limonoids (1–3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. Three new phragmalin-type limonoids (1–3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. The structures of these compounds were established on the basis of spectroscopic data. All these isolates were evaluated for their anti-feedant activities in tobacco caterpillar (Spodoptera litura) and castor semilooper (Achaea janata) using a no-choice laboratory bioassay. Among the tested, compounds 9 and 15 demonstrated the potent anti-feedant index (76.46μg/cm2, 66.61μg/cm2 against A. janata, and 61.69μg/cm2, 51.93μg/cm2against S. litura).
ISSN:0960-894X
1464-3405
DOI:10.1016/j.bmcl.2013.12.077