Assessment of relationship on excess fluoride intake from drinking water and carotid atherosclerosis development in adults in fluoride endemic areas, China

Cross-sectional analysis was conducted to access the relationships between developing carotid artery atherosclerosis through consuming high fluoride in drinking water and its possible mechanism, using the baseline data collected from 585 study subjects. In the cross sectional analysis, subjects were...

Full description

Saved in:
Bibliographic Details
Published in:International journal of hygiene and environmental health 2014-03, Vol.217 (2-3), p.413-420
Main Authors: Liu, Hui, Gao, Yanhui, Sun, Liyan, Li, Mang, Li, Bingyun, Sun, Dianjun
Format: Article
Language:English
Subjects:
Adults
Aged
Air. Soil. Water. Waste. Feeding
Atherosclerosis
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Carotid Arteries - drug effects
Carotid Arteries - pathology
Carotid Artery Diseases - blood
Carotid Artery Diseases - chemically induced
China
Cross-Sectional Studies
Drinking water
Drinking Water - chemistry
Environment. Living conditions
Environmental Exposure - adverse effects
Environmental Exposure - analysis
Epidemiology
Excess fluoride intake
Female
Fluorides - adverse effects
Fluorides - analysis
General aspects
Glutathione Peroxidase - blood
Humans
Intercellular Adhesion Molecule-1 - blood
Male
Medical sciences
Middle Aged
Public health. Hygiene
Public health. Hygiene-occupational medicine
Toxicology
Water Supply
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cross-sectional analysis was conducted to access the relationships between developing carotid artery atherosclerosis through consuming high fluoride in drinking water and its possible mechanism, using the baseline data collected from 585 study subjects. In the cross sectional analysis, subjects were divided into four groups based on the concentrations of fluoride in their drinking water. The range of fluoride concentrations was: normal group (less than 1.20mg/L), mild group (1.21–2.00mg/L), moderate group (2.01–3.00mg/L), and high concentration group (more than 3.01mg/L). The prevalence rate of carotid artery atherosclerosis in the subjects in each group was found to be 16.13%, 27.22%, 27.10%, and 29.69%, respectively. Significant difference between the prevalence of carotid artery atherosclerosis in the mild, moderate and high fluoride exposure group and in the normal group was observed (P
ISSN:1438-4639
1618-131X
DOI:10.1016/j.ijheh.2013.08.001