Reliability of pulse oximetry in hypoxic newborn pigs

Abstract Objective: The reliability of pulse oximetry in the lower SaO2-ranges has not been fully investigated. We wanted to investigate pulse oximeter performance in a pig model of perinatal asphyxia. Methods: Asphyxia was induced in 22 newborn pigs. Pulse oximetry-values for SpO2, as well as SaO2...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2014-05, Vol.27 (8), p.833-838
Main Authors: Solevåg, Anne Lee, Dannevig, Ingrid, Šaltyt -Benth, J rat, Saugstad, Ola D., Nakstad, Britt
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
Asphyxia - blood
Blood Gas Analysis
Hypoxia
Hypoxia - blood
newborn
Oximetry - methods
Oximetry - standards
Oximetry - statistics & numerical data
Oxygen - blood
Reproducibility of Results
Swine
Time Factors
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Summary:Abstract Objective: The reliability of pulse oximetry in the lower SaO2-ranges has not been fully investigated. We wanted to investigate pulse oximeter performance in a pig model of perinatal asphyxia. Methods: Asphyxia was induced in 22 newborn pigs. Pulse oximetry-values for SpO2, as well as SaO2 from blood gas analyses were recorded multiple times before, during and after asphyxiation. The relationship between SpO2 and SaO2 in normoxia and hypoxia in this model was quantified. Calculations were made for 5% increments of SaO2 increasing successively from 95% to 20%. Results: The pigs became severely hypoxic, acidotic and hypotensive. The bias in the total data was +13.7 (p 
ISSN:1476-7058
1476-4954
DOI:10.3109/14767058.2013.842550