Correlation between atherogenic risk and adiponectin in gestational diabetes mellitus

Gestational diabetes mellitus (GDM) is a pregnancy complication which increases the risk for maternal and foetal complications during pregnancy, and also significantly increases the cardiovascular risk for women's health in the postpartum. Current literature provides contradictory information o...

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Bibliographic Details
Published in:Annals of Agricultural and Environmental Medicine 2014, Vol.21 (1), p.143-147
Main Authors: Matyjaszek-Matuszek, Beata, Lenart-Lipińska, Monika, Kowalczyk-Bołtuć, Jolanta, Szlichtyng, Wojciech, Paszkowski, Tomasz
Format: Article
Language:English
Subjects:
Adiponectin
Adiponectin - blood
Adult
Atherosclerosis - blood
Atherosclerosis - diagnosis
Atherosclerosis - epidemiology
Atherosclerosis - etiology
Blood Chemical Analysis
Blood levels
C-reactive protein
Cardiovascular diseases
Cholesterol
Diabetes mellitus
Diabetes, Gestational - blood
Diabetes, Gestational - epidemiology
Diabetes, Gestational - etiology
Enzyme-Linked Immunosorbent Assay
Female
Fibrinogen
Gestation
Gestational diabetes
Health risks
Humans
Incidence
Insulin
Insulin resistance
Laboratories
Laboratory tests
Neonates
Poland
Pregnancy
Pregnancy complications
Prevalence
Risk Factors
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Summary:Gestational diabetes mellitus (GDM) is a pregnancy complication which increases the risk for maternal and foetal complications during pregnancy, and also significantly increases the cardiovascular risk for women's health in the postpartum. Current literature provides contradictory information on the role of adiponectin (AdipoQ) in the course of GDM. The aim of the study was to measure AdipoQ concentration in blood of women with GDM and to find correlations between this adipokine and clinical and biochemical parameters of the atherogenic risk. The GDM group included 50 women diagnosed with GDM between 24 - 28 weeks of gestation who underwent routine prenatal tests for GDM in compliance with the guidelines of the Polish Diabetes Association. All patients underwent clinical and laboratory evaluation at GDM diagnosis. Laboratory tests included serum AdipoQ concentration, fasting glucose and insulin, OGTT, lipid parameters, C-reactive protein and fibrinogen in serum. The GDM group showed significantly elevated fasting glucose, insulin, HOMA-IR values, total cholesterol, LDLcholesterol and triglicerydes as compared with the control group (p
ISSN:1232-1966
1898-2263