Correlates of self-reported quality of life in adults and children with morphea

Background Determining a disease's impact on life quality is important in clinical decision making, research, and resource allocation. Determinants of quality of life (QOL) in morphea are poorly understood. Objective We sought to ascertain demographic and clinical variables correlated with nega...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2014-05, Vol.70 (5), p.904-910
Main Authors: Das, Shinjita, MD, Bernstein, Ira, PhD, Jacobe, Heidi, MD, MSCS
Format: Article
Language:English
Subjects:
Adult
Child
Cohort Studies
Cross-Sectional Studies
Dermatology
Female
Humans
life quality or quality of life
localized scleroderma
Male
morphea
Morphea in Adults and Children cohort
outcomes or disease outcomes
Quality of Life
Scleroderma, Localized - classification
Scleroderma, Localized - diagnosis
Scleroderma, Localized - therapy
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Determining a disease's impact on life quality is important in clinical decision making, research, and resource allocation. Determinants of quality of life (QOL) in morphea are poorly understood. Objective We sought to ascertain demographic and clinical variables correlated with negative impact on self-reported QOL in morphea. Methods We conducted a cross-sectional survey of the Morphea in Adults and Children cohort. Results Symptoms (pruritus and pain) and functional impairment were correlated with decreased QOL in children and adults. This was true in both sexes and was independent of subtype and age. Patient-reported QOL correlated with physician-based measures of disease severity in adults, but not in children. Patients with linear and generalized morphea had the greatest impact on QOL. Limitations Small sample size is a limitation. Conclusion Symptoms and functional impairment were determinants of impaired life quality in both children and adults independent of morphea subtype. These results suggest that clinicians should consider suppressing the accumulation of new lesions (when rapidly accumulating) and symptoms (pain and pruritus) in the treatment of patients with morphea.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2013.11.037