Vertebral body replacement with PEEK-cages after anterior corpectomy in multilevel cervical spinal stenosis: a clinical and radiological evaluation

• Published in: Archives of orthopaedic and trauma surgery 2014-05, Vol.134 (5), p.611-618
• Main Authors: Raslan, Furat, Koehler, Stefan, Berg, Frank, Rueckriegel, Stefan, Ernestus, Ralf-Ingo, Meinhardt, Matthias, Westermaier, Thomas
• Format: Article
• Language: English
• Subjects: Adult; Aged; Biocompatible Materials; Bone Plates; Bone Screws; Cervical Vertebrae - surgery; Decompression, Surgical - instrumentation; Diskectomy - methods; Female; Humans; Ketones; Male; Medicine; Medicine & Public Health; Middle Aged; Orthopaedic Surgery; Orthopedics; Polyethylene Glycols; Prostheses and Implants; Prosthesis Design; Reoperation; Retrospective Studies; Spinal Cord Diseases - surgery; Spinal Fusion - instrumentation; Spinal Fusion - methods; Spinal stenosis; Spinal Stenosis - surgery; Tomography, X-Ray Computed
• ISSN: 0936-8051; 1434-3916
• DOI: 10.1007/s00402-014-1972-1

Introduction A growing number of industrially manufactured implants have been developed in the last years for vertebral replacement in anterior cervical corpectomy and fusion (ACCF). Polyetheretherketone (PEEK)-cages are used in many centers, but outcome reports are scarce. This study assesses the clinical and radiological outcome after one- or two-level ACCF by the use of a PEEK-cage augmented by a plate–screw osteosynthesis. Methods A total of 21 patients received one-level (18 patients) or two-level (3 patients) ACCF by a PEEK-cage and plate–screw osteosynthesis for multilevel degenerative stenosis. The Visual Analogue Scale, Nurick Score, Neck Disability Index and European Myelopathy Score were used for clinical assessment. Radiological outcome—osseous fusion and loss of height—was evaluated by CT. Results The mean follow-up was 28 ± 12 months. In 19 patients, bony fusion was achieved after the primary operation. Graft failure that required surgical revision occurred in two patients. In these patients, osseous fusion was achieved after the second operation. Myelopathy improved significantly. The loss of height was 2.2 ± 2.3 and 5.3 ± 2.1 mm after one- and two-level ACCF, respectively. Conclusion Anterior corpectomy and fusion by a PEEK-cage and plate–screw osteosynthesis resulted in clinical improvement in all patients. Bony fusion was achieved in all patients in the long run. PEEK cages are allegedly less rigid than other xenografts. Similar to those, however, their use bears the risk of early cage-dislocation and subsidence. A comparison of industrial xenografts and autologous bone implants is required to challenge the different fusion techniques.