Levels of lethal antibody during the course of infection with Schistosoma mansoni in rats and mice

Schistosoma mansoni infected hosts produce an IgG that mediates the complement-dependent killing of schistosomula in vitro. In this study, the authors followed the levels of serum lethal antibody during infection of rats and mice. They correlate lethal antibody and protective immunity suggesting tha...

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Bibliographic Details
Published in:Memórias do Instituto Oswaldo Cruz 1987-01, Vol.82, p.no. sul.-no. sul.
Main Authors: Horta, MFM, Ramalho-Pinto, F J
Format: Article
Language:English
Subjects:
Schistosoma mansoni
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Summary:Schistosoma mansoni infected hosts produce an IgG that mediates the complement-dependent killing of schistosomula in vitro. In this study, the authors followed the levels of serum lethal antibody during infection of rats and mice. They correlate lethal antibody and protective immunity suggesting that the antibody-mediated complement-dependent cytotoxicity to schistosomula play a role in the immunity to reinfection.
ISSN:0074-0276