Benefit from synchronous portal-superior mesenteric vein resection during pancreaticoduodenectomy for cancer: A meta-analysis

Abstract Background Pancreaticoduodenectomy combined with portal-superior mesenteric vein synchronous resection for cancer remains a hot debate topic. The present study used meta-analytical technique to provide update information and an evidence-based evaluation on both the perioperative benefit and...

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Bibliographic Details
Published in:European journal of surgical oncology 2014-04, Vol.40 (4), p.371-378
Main Authors: Yu, X.Z, Li, J, Fu, D.L, Di, Y, Yang, F, Hao, S.J, Jin, C
Format: Article
Language:English
Subjects:
Evidence-Based Medicine
Hematology, Oncology and Palliative Medicine
Humans
Lymphatic Metastasis
Mesenteric Veins - pathology
Mesenteric Veins - surgery
Meta-analysis
Morbidity
Pancreatic Neoplasms - mortality
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - surgery
Pancreaticoduodenectomy
Pancreaticoduodenectomy - adverse effects
Pancreaticoduodenectomy - methods
Perioperative Period
Portal Vein - pathology
Portal Vein - surgery
PV/SMV resection
R0 resection
Retrospective Studies
Surgery
Survival Analysis
Treatment Outcome
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Summary:Abstract Background Pancreaticoduodenectomy combined with portal-superior mesenteric vein synchronous resection for cancer remains a hot debate topic. The present study used meta-analytical technique to provide update information and an evidence-based evaluation on both the perioperative benefit and long-term survival. Methods A meta-analysis was performed to evaluate studies comparing venous resection (VR) versus without venous resection (WVR) groups. 22 retrospective studies including 2890 patients were eligible for an analysis of perioperative morbidity, mortality, and long-term survival. Furthermore, subgroup analysis was made according to histopathology and resection margin status respectively for the purpose of survival assessment. Results There was no difference in perioperative morbidity, mortality and 1-year, 3-year survival between two groups, but showed differences in median tumor size ( P  
ISSN:0748-7983
1532-2157
DOI:10.1016/j.ejso.2014.01.010