Restoration of the coagulation cascade on CPB: a case report

Coagulopathy can sometimes be observed when CPB times are prolonged. Correction of coagulopathy post CPB can present the surgical team with a number of challenges, including right ventricular volume overload, hemodilution, anemia and excessive cell salvage with further loss of coagulation factors. R...

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Bibliographic Details
Published in:Perfusion 2014-05, Vol.29 (3), p.272-274
Main Authors: Lilly, KJ, Pirundini, PA, Fox, AA, Body, SC, Shaw, C, Rizzo, RJ
Format: Article
Language:English
Subjects:
Blood Coagulation
Blood Coagulation Factors
Blood Component Transfusion
Cardiopulmonary Bypass
Disseminated Intravascular Coagulation - blood
Disseminated Intravascular Coagulation - etiology
Disseminated Intravascular Coagulation - metabolism
Disseminated Intravascular Coagulation - therapy
Humans
Middle Aged
Plasma
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Summary:Coagulopathy can sometimes be observed when CPB times are prolonged. Correction of coagulopathy post CPB can present the surgical team with a number of challenges, including right ventricular volume overload, hemodilution, anemia and excessive cell salvage with further loss of coagulation factors. Restoration of the coagulation cascade on CPB may help to avoid these issues. This case report is of a 64-year-old male with a delayed diagnosis of aortic dissection. The patient presented to the cardiac surgery operating room with hepatic and renal shock/failure, with the resulting coagulopathy. The described technique is representative of a technique that we sometimes employ to restore the clotting mechanism before separating from bypass.
ISSN:0267-6591
1477-111X
DOI:10.1177/0267659113507471