Calf circumference, frailty and physical performance among older adults living in the community

• Published in: Clinical nutrition (Edinburgh, Scotland) Scotland), 2014-06, Vol.33 (3), p.539-544
• Main Authors: Landi, Francesco, Onder, Graziano, Russo, Andrea, Liperoti, Rosa, Tosato, Matteo, Martone, Anna Maria, Capoluongo, Ettore, Bernabei, Roberto
• Format: Article
• Language: English
• Subjects: Activities of Daily Living; Aged, 80 and over; Aging - physiology; Biological and medical sciences; Body Composition; Body Mass Index; Calf circumference; Feeding. Feeding behavior; Female; Frail Elderly; Fundamental and applied biological sciences. Psychology; Gastroenterology and Hepatology; Geriatric Assessment; Hand Strength; Humans; Leg - anatomy & histology; Longevity - physiology; Male; Muscle Strength - physiology; Physical performance; Prospective Studies; Residence Characteristics; Surveys and Questionnaires; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Walking
• ISSN: 0261-5614; 1532-1983
• DOI: 10.1016/j.clnu.2013.07.013

Summary Background & aims Lean body mass loss has been indicated as a reliable marker of frailty and poor physical performance among older individuals. We evaluated the relationship between calf circumference and frailty, physical performance, muscle strength, and functional status in persons aged 80 years or older. Methods Data are from the baseline evaluation of the Aging and Longevity Study in the Sirente geographic area (ilSIRENTE Study) ( n  = 357). The calf circumference was measured at the point of greatest circumference. Frailty was categorized according to the present of slow gait speed, weakness, weight loss, energy expenditure and exhaustion. Physical performance was assessed using the physical performance battery score, which is based on three timed tests: 4-m walking speed test, the balance test and the chair stand test. Analyses of covariance were performed to evaluate the relationship between different calf circumference and physical function. Results After adjustment for potential confounders, which included age, gender, education, body mass index, sensory impairments, cerebrovascular diseases, albumin, reactive C protein, interleukine-6, and cholesterol, physical performance (SPPB score: 7.27 versus 6.18, p  = 0.02) and muscle strength (Hand Grip: 32 kg versus 28 kg, p  = 0.03) measures significantly improved as calf circumference increased. The frailty index score was significantly lower among subjects with higher calf circumference (1.66 versus 2.17, p  = 0.01). Conclusions The present study suggests that among community-dwelling older people, calf circumference may be positively related to lower frailty index and higher functional performance. As such, calf circumference is a valuable tool for guiding public health policy and clinical decisions.