CD4 super(+)and CD8 super(+)T-cell reactions against leukemia-associated- or minor-histocompatibility-antigens in AML-patients after allogeneic SCT

T-cells play an important role in the remission-maintenance in AML-patients (pts) after SCT, however the role of LAA- (WT1, PR1, PRAME) or minor-histocompatibility (mHag, HA1) antigen-specific CD4 super(+) and CD8 super(+)T-cells is not defined.

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Bibliographic Details
Published in:Immunobiology (1979) 2014-04, Vol.219 (4), p.247-260
Main Authors: Steger, Brigitte, Milosevic, Slavoljub, Doessinger, Georg, Reuther, Susanne, Liepert, Anja, Braeu, Marion, Schick, Julia, Vogt, Valentin, Schuster, Friedhelm, Kroell, Tanja, Busch, Dirk H, Borkhardt, Arndt, Kolb, Hans-Jochem, Tischer, Johanna, Buhmann, Raymund, Schmetzer, Helga
Format: Article
Language:English
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Summary:T-cells play an important role in the remission-maintenance in AML-patients (pts) after SCT, however the role of LAA- (WT1, PR1, PRAME) or minor-histocompatibility (mHag, HA1) antigen-specific CD4 super(+) and CD8 super(+)T-cells is not defined.
ISSN:0171-2985
DOI:10.1016/j.imbio.2013.10.008