Assessment of dietary intake of fumonisin B1 in São Paulo, Brazil

• Published in: Food chemistry 2014-07, Vol.155, p.174-178
• Main Authors: Bordin, K., Rosim, R.E., Neeff, D.V., Rottinghaus, G.E., Oliveira, C.A.F.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Biological and medical sciences; Brazil; Child; Corn-based products; Diet; Estimation of intake; Family Characteristics; FB1; Female; Food Contamination - analysis; Fumonisins - analysis; Fumonisins - metabolism; Humans; Male; Medical sciences; Middle Aged; Mycotoxins - analysis; Mycotoxins - metabolism; Plant poisons toxicology; Toxicology; Young Adult; Zea mays - chemistry; Zea mays - metabolism
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2014.01.057

•Fumonisin B1 (FB1) was determined in 120 samples of corn products in São Paulo, Brazil.•The highest levels of FB1 were found in corn meal at a mean concentration of 474.6μgkg−1.•Mean PDI of FB1 estimated by FFQ and foods analyzed was nearly 3% of the PMTDI recommended.•The consumption data indicate a low human exposure to FB1 in the population studied. In this study, fumonisin B1 (FB1) consumption was assessed through determination of FB1 in corn meal, corn flour, corn flakes, polenta, canned corn and popcorn collected from homes of residents of Pirassununga, São Paulo, Brazil, and using a Food Frequency Questionnaire (FFQ) filled out by the residents. One hundred and twenty samples were collected from 39 residents on four separate occasions. FB1 was determined by high performance liquid chromatography using a validated method that uses SAX column clean-up. The highest levels of FB1 were found in corn meal at a mean concentration of 474.6μgkg−1. However, none of the samples tested for FB1 had levels above the tolerance limit established in Brazil. The mean probable daily intake (PDIM) of FB1 was 63.3ngkg−1bodyweightday−1, which is approximately 3% of the provisional maximum tolerable daily intake (PMTDI) recommended for fumonisins.