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Intracellular distribution of the vitamin D receptor in the brain: Comparison with classic target tissues and redistribution with development

Highlights • The vitamin D receptor (VDR) is present in the rodent brain. • In the embryo, in the three tissues studied VDR is primarily nuclear. • Adult VDR is nuclear in the brain, but is also found in cell membranes in the gut and kidney. • VDR expression is lower in the brain compared to classic...

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Bibliographic Details
Published in:Neuroscience 2014-05, Vol.268, p.1-9
Main Authors: Eyles, D.W, Liu, P.Y, Josh, P, Cui, X
Format: Article
Language:English
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Summary:Highlights • The vitamin D receptor (VDR) is present in the rodent brain. • In the embryo, in the three tissues studied VDR is primarily nuclear. • Adult VDR is nuclear in the brain, but is also found in cell membranes in the gut and kidney. • VDR expression is lower in the brain compared to classic VDR targets i.e. the gut and kidney.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2014.02.042