Value of Preoperative Inflammation-Based Prognostic Scores in Predicting Overall Survival and Disease-Free Survival in Patients with Gastric Cancer

Background This study was designed to identify which are the best preoperative inflammation-based prognostic scores in terms of overall survival (OS) and disease-free survival (DFS) in patients with gastric cancer. Methods Between January 2004 and January 2013, 102 consecutive patients underwent res...

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Bibliographic Details
Published in:Annals of surgical oncology 2014-06, Vol.21 (6), p.1998-2004
Main Authors: Aurello, Paolo, Tierno, Simone Maria, Berardi, Giammauro, Tomassini, Federico, Magistri, Paolo, D’Angelo, Francesco, Ramacciato, Giovanni
Format: Article
Language:English
Subjects:
Aged
C-Reactive Protein - metabolism
CA-19-9 Antigen - blood
Carcinoembryonic Antigen - blood
Disease-Free Survival
Female
Gastrointestinal Oncology
Humans
Inflammation - blood
Lymph Nodes - pathology
Lymphatic Metastasis
Lymphocyte Count
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Grading
Neoplasm Staging
Neoplasm, Residual
Neutrophils
Oncology
Platelet Count
Predictive Value of Tests
Preoperative Care
Retrospective Studies
Serum Albumin - metabolism
Stomach Neoplasms - blood
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Surgery
Surgical Oncology
Survival Rate
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Summary:Background This study was designed to identify which are the best preoperative inflammation-based prognostic scores in terms of overall survival (OS) and disease-free survival (DFS) in patients with gastric cancer. Methods Between January 2004 and January 2013, 102 consecutive patients underwent resection for gastric cancer at S. Andrea Hospital, "La Sapienza", University of Rome. Their records were retrospectively reviewed. Results After a median follow up of 40.8 months (8–107 months), patients’ 1-, 3-, and 5-year OS rates were 88, 72, and 59 %, respectively. After R0 resection, the 1-, 3-, and 5-year DFS rates were 93, 74, and 56 %, respectively. A multivariate analysis of the significant variables showed that only the modified Glasgow prognostic scores ( p  
ISSN:1068-9265
1534-4681
DOI:10.1245/s10434-014-3533-9