Value of EQ-5D in Mexican city older population with and without dementia (SADEM study)

• Published in: International journal of geriatric psychiatry 2014-05, Vol.29 (5), p.478-488
• Main Authors: Sanchez-Arenas, Rosalinda, Vargas-Alarcon, Gilberto, Sanchez-Garcia, Sergio, Garcia-Peña, Carmen, Gutierrez-Gutierrez, Lidia, Grijalva, Israel, Garcia-Dominguez, Angelica, Juárez-Cedillo, Teresa
• Format: Article
• Language: English
• Subjects: Activities of Daily Living; Aged; Aged, 80 and over; Biological and medical sciences; Brief Psychiatric Rating Scale; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dementia; Dementia - diagnosis; Dementia - psychology; General aspects; Geriatric Assessment - methods; Geriatric psychiatry; Geriatrics; health state valuations; Health Status; Health Status Indicators; Humans; Male; Medical sciences; Mexico; Middle Aged; Neurology; Older people; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Quality of Life; quality of life EQ-5D; Reliability; Reproducibility of Results; Surveys and Questionnaires - standards
• ISSN: 0885-6230; 1099-1166
• DOI: 10.1002/gps.4030

Background The EuroQoL‐5D (EQ‐5D) is a brief, multi‐attribute, preference‐based health status measurement. The objective of this study was to assess the validity and reliability of EQ‐5D in older adults with and without dementia in Mexico City. Methods The Study on Aging and Dementia in Mexico (SADEM) was a survey of 3101, Mexican adults (60 + years old). An in‐home face‐to‐face interview was administered. EQ‐5D using ranking to rate states on a 100‐point visual analogue scale; Daily Living Activities (ADL), Instrumental Activities of Daily Living (IADL), Mini Mental State Examination (MMSE), Short Form of the quality of life survey (SF‐36), and Charlson comorbility index were used for comparison. The validity and reliability of EQ‐5D were tested. We identified states of health for direct valuation; state 11111 (“no problems”) had to be included because it was essential to the reseating (onto a 0–1 scale) of the visual analogue scale data. We included all plausible combinations of levels across each of the five EQ‐5D dimensions and evaluated any significant interaction effects and factorial designs, based on balanced complete blocks. Results The EQ‐5D was applied to 3101 older people, of whom 109 (3.4%) had dementia. The general reliability of EQ‐5D for cases was 0.80 and for controls 0.76, for each dimension. We had a total of 103 combinations for controls and 45 for cases. The percentage for the state of health “no problems” (11111) for controls was 30.4%, and had the highest percentage of cases (8.8%). Conclusion The resulting valuations form the basis for clinical use and facilitate the interpretation and evaluation of health care. Copyright © 2013 John Wiley & Sons, Ltd.