Reduced incidence of invasive pneumococcal disease after introduction of the 13-valent conjugate vaccine in Navarre, Spain, 2001–2013

Highlights • We analyse the trend of invasive pneumococcal disease in the 13-valent vaccine era. • The incidence of cases has declined notably in children and moderately in adults. • The incidence of cases due to vaccine serotypes decreased 81% in children

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Bibliographic Details
Published in:Vaccine 2014-05, Vol.32 (22), p.2553-2562
Main Authors: Guevara, Marcela, Ezpeleta, Carmen, Gil-Setas, Alberto, Torroba, Luis, Beristain, Xabier, Aguinaga, Aitziber, García-Irure, José Javier, Navascués, Ana, García-Cenoz, Manuel, Castilla, Jesús
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Allergy and Immunology
Applied microbiology
Bacterial diseases
Bacteriology
Biological and medical sciences
Child
Child, Preschool
Children & youth
Female
Fundamental and applied biological sciences. Psychology
Human bacterial diseases
Humans
Immunization
Impact
Incidence
Infant
Infectious diseases
Invasive pneumococcal disease
Male
Medical sciences
Meningitis
Microbiology
Middle Aged
Miscellaneous
Pneumococcal conjugate vaccine
Pneumococcal Infections - epidemiology
Pneumococcal Infections - prevention & control
Pneumococcal Vaccines - administration & dosage
Pneumonia
Public health surveillance
Sentinel Surveillance
Spain - epidemiology
Staphylococcal infections, streptococcal infections, pneumococcal infections
Streptococcus pneumoniae
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Vaccines, Conjugate - administration & dosage
Young Adult
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Description
Summary:Highlights • We analyse the trend of invasive pneumococcal disease in the 13-valent vaccine era. • The incidence of cases has declined notably in children and moderately in adults. • The incidence of cases due to vaccine serotypes decreased 81% in children
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2014.03.054