The G allele at the g.70014208A>G in the MYBPC1 gene associated with high marbling in Japanese Black cattle is at a low frequency in breeds not selected for marbling

A single nucleotide polymorphism (SNP), g.70014208A>G in the promoter region of the myosin binding protein C, slow type (MYBPC1) gene is associated with marbling in Japanese Black beef cattle. We investigated the allele frequency distribution of the g.70014208A>G SNP among the ve cattle breeds...

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Bibliographic Details
Published in:Journal of genetics 2014-04, Vol.93 (1), p.231-233
Main Authors: TONG, BIN, SASAKI, SEIKI, MURAMATSU, YOUJI, OHTA, TAKESHI, KOSE, HIROYUKI, FUJITA, TATSUO, YAMADA, TAKAHISA
Format: Article
Language:English
Subjects:
Alleles
Animal Genetics and Genomics
Animals
Biomedical and Life Sciences
Breeding
Carrier Proteins - genetics
Cattle
Evolutionary Biology
Frequency distribution
Gene Frequency
Genes
Life Sciences
Microbial Genetics and Genomics
Plant Genetics and Genomics
Polymorphism
Polymorphism, Single Nucleotide
Quantitative Trait, Heritable
Research Note
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Summary:A single nucleotide polymorphism (SNP), g.70014208A>G in the promoter region of the myosin binding protein C, slow type (MYBPC1) gene is associated with marbling in Japanese Black beef cattle. We investigated the allele frequency distribution of the g.70014208A>G SNP among the ve cattle breeds, Japanese Black, Japanese Brown, Japanese Short Horn, Holstein and Brown Swiss breeds. As compared to the frequency of the g.70014208A>GG allele associated with high marbling in Japanese Black breed that has been subjected to a strong selection for high marbling, those in the other breeds that have not been strongly selected for high marbling were null or lower. Thus, we hypothesized that the pressure of the strong selection for high marbling in Japanese Black breed has increased the frequency of the G allele at theg.70014208A>G SNP in the MYBPC1.
ISSN:0022-1333
0973-7731
DOI:10.1007/s12041-014-0353-4