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Informing Drug Development and Clinical Practice Through Patient-Centered Outcomes Research

[...]in measuring the impact of irritable bowel syndrome on quality of life, Andrae et al5 used item response theory to ensure that the PRO instrument's scoring algorithm is most reflective of the patient perception of quality of life. [...]Edelen et al6 also applied item response theory to the...

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Bibliographic Details
Published in:Clinical therapeutics 2014-05, Vol.36 (5), p.616-618
Main Authors: Coon, Cheryl D., PhD, Lau, Denys T., PhD
Format: Article
Language:English
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Summary:[...]in measuring the impact of irritable bowel syndrome on quality of life, Andrae et al5 used item response theory to ensure that the PRO instrument's scoring algorithm is most reflective of the patient perception of quality of life. [...]Edelen et al6 also applied item response theory to their research in asthma, with the goal of scoring separate PRO instruments on a common metric; in doing so, this method may aid researchers in comparing the results of separate studies to gain a broader picture of the patient experience and to compare the efficacy of different therapies that may not be assessed head-to-head.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2014.04.015