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Sonochemistry: A good, fast and clean method to promote the synthesis of 5-arylidene-2,4-thiazolidinediones

•Sixteen 5-arylidene-2,4-thiazolidinediones were synthesized by ultrasound irradiation.•The desire products were obtained in short reaction times (10–30min).•Ultrasound irradiation is efficient to aldol condensation reaction. The efficient synthesis of sixteen 5-arylidene-2,4-thiazolidinediones by a...

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Bibliographic Details
Published in:Ultrasonics sonochemistry 2014-09, Vol.21 (5), p.1615-1617
Main Authors: Drawanz, Bruna B., Ribeiro, Camila S., Masteloto, Hellen G., Neuenfeldt, Patrícia D., Pereira, Claudio M.P., Siqueira, Geonir M., Cunico, Wilson
Format: Article
Language:English
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Summary:•Sixteen 5-arylidene-2,4-thiazolidinediones were synthesized by ultrasound irradiation.•The desire products were obtained in short reaction times (10–30min).•Ultrasound irradiation is efficient to aldol condensation reaction. The efficient synthesis of sixteen 5-arylidene-2,4-thiazolidinediones by aldol condensation reaction of 2,4-thiazolidinedione, mono- and di-substituted arenealdehydes and KOH using ultrasound irradiation is reported. The desired compounds were obtained in a few min (10–30min) with moderate to good yields (25–81%).
ISSN:1350-4177
1873-2828
DOI:10.1016/j.ultsonch.2014.04.013