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Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma
Purpose To describe a new technique to perform trabeculotomy ab interno on eyes with open-angle glaucoma (OAG). Methods This was a retrospective study. We inserted a 25-gauge forceps that is usually used for internal limiting membrane peeling into the anterior chamber, and grasped and pulled the inn...
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| Published in: | Graefe's archive for clinical and experimental ophthalmology 2014-06, Vol.252 (6), p.977-982 |
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| container_title | Graefe's archive for clinical and experimental ophthalmology |
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| creator | Nakasato, Houmei Uemoto, Riyo Isozaki, Masaru Meguro, Akira Kawagoe, Tatsukata Mizuki, Nobuhisa |
| description | Purpose
To describe a new technique to perform trabeculotomy
ab interno
on eyes with open-angle glaucoma (OAG).
Methods
This was a retrospective study. We inserted a 25-gauge forceps that is usually used for internal limiting membrane peeling into the anterior chamber, and grasped and pulled the inner wall of Schlemm’s canal away from the canal. The inner wall of Schlemm’s canal was stripped for about 100° to 120° in 26 eyes of 23 patients. The intraocular pressure (IOP) and number of glaucoma medications were recorded before, and 1 day, 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. The intra- and postoperative complications were recorded.
Results
The mean ± standard deviation of the preoperative IOP was 20.0 ± 6.8 mmHg with a range from 10 to 38 mmHg (
n
= 26). The IOP was significantly reduced (
P
|
| doi_str_mv | 10.1007/s00417-014-2616-4 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1530319461</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1530319461</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-cafb8edba587627da334b4c07e7f2e7a57244ef0d8efe89a438715956b8336f23</originalsourceid><addsrcrecordid>eNp1kE1LxDAQhoMo7rr6A7xIwYuXaL7aZI-y-AULXlbYW0jaae3SNjVpkf33tnQVETwNYZ55Z_IgdEnJLSVE3gVCBJWYUIFZQhMsjtCcCh5jSdj2GM2JZBQrzrYzdBbCjgw4j-kpmjGRJIorOUfbjTcW0r5ynav3kbFR2XTgGxd9lt374WGqqCrrsiubIqqhtt40EOXOp9CGsUauhQabpqggKirTp6425-gkN1WAi0NdoLfHh83qGa9fn15W92uccsk6nJrcKsisiZVMmMwM58KKlEiQOQNpYsmEgJxkCnJQSyOGq2m8jBOrOE9yxhfoZsptvfvoIXS6LkMKVTXc6PqgacwJp0uR0AG9_oPuXD_-7psijI4UnajUuxA85Lr1ZW38XlOiR-160q4H7XrUrsUwc3VI7m0N2c_Et-cBYBMQhlZTgP-1-t_UL254jY8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1530310211</pqid></control><display><type>article</type><title>Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma</title><source>Springer Link</source><creator>Nakasato, Houmei ; Uemoto, Riyo ; Isozaki, Masaru ; Meguro, Akira ; Kawagoe, Tatsukata ; Mizuki, Nobuhisa</creator><creatorcontrib>Nakasato, Houmei ; Uemoto, Riyo ; Isozaki, Masaru ; Meguro, Akira ; Kawagoe, Tatsukata ; Mizuki, Nobuhisa</creatorcontrib><description>Purpose
To describe a new technique to perform trabeculotomy
ab interno
on eyes with open-angle glaucoma (OAG).
Methods
This was a retrospective study. We inserted a 25-gauge forceps that is usually used for internal limiting membrane peeling into the anterior chamber, and grasped and pulled the inner wall of Schlemm’s canal away from the canal. The inner wall of Schlemm’s canal was stripped for about 100° to 120° in 26 eyes of 23 patients. The intraocular pressure (IOP) and number of glaucoma medications were recorded before, and 1 day, 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. The intra- and postoperative complications were recorded.
Results
The mean ± standard deviation of the preoperative IOP was 20.0 ± 6.8 mmHg with a range from 10 to 38 mmHg (
n
= 26). The IOP was significantly reduced (
P
< 0.05; paired
t
-tests) at 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 24, 19, 27, 30, and 33 months after the surgery. The mean preoperative number of glaucoma medications was significantly reduced (
P
< 0.001; paired
t
-tests) at 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. No vision-threatening complications were found in any of the cases, but there were blood clots in the anterior chamber postoperatively in 92.3 % of the cases.
Conclusions
Trabeculotomy
ab interno
for OAG is effective but with some minor complications. A larger number of patients with longer follow-up periods are needed to determine the long-term effectiveness of this procedure.</description><identifier>ISSN: 0721-832X</identifier><identifier>EISSN: 1435-702X</identifier><identifier>DOI: 10.1007/s00417-014-2616-4</identifier><identifier>PMID: 24668387</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Aged ; Antihypertensive Agents - administration & dosage ; Female ; Follow-Up Studies ; Glaucoma ; Glaucoma, Open-Angle - physiopathology ; Glaucoma, Open-Angle - surgery ; Humans ; Intraocular Pressure - physiology ; Intraoperative Complications ; Male ; Medicine ; Medicine & Public Health ; Ophthalmology ; Phacoemulsification ; Postoperative Complications ; Retrospective Studies ; Tonometry, Ocular ; Trabeculectomy - instrumentation ; Trabeculectomy - methods ; Visual Acuity - physiology</subject><ispartof>Graefe's archive for clinical and experimental ophthalmology, 2014-06, Vol.252 (6), p.977-982</ispartof><rights>Springer-Verlag Berlin Heidelberg 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-cafb8edba587627da334b4c07e7f2e7a57244ef0d8efe89a438715956b8336f23</citedby><cites>FETCH-LOGICAL-c372t-cafb8edba587627da334b4c07e7f2e7a57244ef0d8efe89a438715956b8336f23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24668387$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakasato, Houmei</creatorcontrib><creatorcontrib>Uemoto, Riyo</creatorcontrib><creatorcontrib>Isozaki, Masaru</creatorcontrib><creatorcontrib>Meguro, Akira</creatorcontrib><creatorcontrib>Kawagoe, Tatsukata</creatorcontrib><creatorcontrib>Mizuki, Nobuhisa</creatorcontrib><title>Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma</title><title>Graefe's archive for clinical and experimental ophthalmology</title><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><description>Purpose
To describe a new technique to perform trabeculotomy
ab interno
on eyes with open-angle glaucoma (OAG).
Methods
This was a retrospective study. We inserted a 25-gauge forceps that is usually used for internal limiting membrane peeling into the anterior chamber, and grasped and pulled the inner wall of Schlemm’s canal away from the canal. The inner wall of Schlemm’s canal was stripped for about 100° to 120° in 26 eyes of 23 patients. The intraocular pressure (IOP) and number of glaucoma medications were recorded before, and 1 day, 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. The intra- and postoperative complications were recorded.
Results
The mean ± standard deviation of the preoperative IOP was 20.0 ± 6.8 mmHg with a range from 10 to 38 mmHg (
n
= 26). The IOP was significantly reduced (
P
< 0.05; paired
t
-tests) at 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 24, 19, 27, 30, and 33 months after the surgery. The mean preoperative number of glaucoma medications was significantly reduced (
P
< 0.001; paired
t
-tests) at 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. No vision-threatening complications were found in any of the cases, but there were blood clots in the anterior chamber postoperatively in 92.3 % of the cases.
Conclusions
Trabeculotomy
ab interno
for OAG is effective but with some minor complications. A larger number of patients with longer follow-up periods are needed to determine the long-term effectiveness of this procedure.</description><subject>Aged</subject><subject>Antihypertensive Agents - administration & dosage</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Glaucoma</subject><subject>Glaucoma, Open-Angle - physiopathology</subject><subject>Glaucoma, Open-Angle - surgery</subject><subject>Humans</subject><subject>Intraocular Pressure - physiology</subject><subject>Intraoperative Complications</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ophthalmology</subject><subject>Phacoemulsification</subject><subject>Postoperative Complications</subject><subject>Retrospective Studies</subject><subject>Tonometry, Ocular</subject><subject>Trabeculectomy - instrumentation</subject><subject>Trabeculectomy - methods</subject><subject>Visual Acuity - physiology</subject><issn>0721-832X</issn><issn>1435-702X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNp1kE1LxDAQhoMo7rr6A7xIwYuXaL7aZI-y-AULXlbYW0jaae3SNjVpkf33tnQVETwNYZ55Z_IgdEnJLSVE3gVCBJWYUIFZQhMsjtCcCh5jSdj2GM2JZBQrzrYzdBbCjgw4j-kpmjGRJIorOUfbjTcW0r5ynav3kbFR2XTgGxd9lt374WGqqCrrsiubIqqhtt40EOXOp9CGsUauhQabpqggKirTp6425-gkN1WAi0NdoLfHh83qGa9fn15W92uccsk6nJrcKsisiZVMmMwM58KKlEiQOQNpYsmEgJxkCnJQSyOGq2m8jBOrOE9yxhfoZsptvfvoIXS6LkMKVTXc6PqgacwJp0uR0AG9_oPuXD_-7psijI4UnajUuxA85Lr1ZW38XlOiR-160q4H7XrUrsUwc3VI7m0N2c_Et-cBYBMQhlZTgP-1-t_UL254jY8</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Nakasato, Houmei</creator><creator>Uemoto, Riyo</creator><creator>Isozaki, Masaru</creator><creator>Meguro, Akira</creator><creator>Kawagoe, Tatsukata</creator><creator>Mizuki, Nobuhisa</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20140601</creationdate><title>Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma</title><author>Nakasato, Houmei ; Uemoto, Riyo ; Isozaki, Masaru ; Meguro, Akira ; Kawagoe, Tatsukata ; Mizuki, Nobuhisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-cafb8edba587627da334b4c07e7f2e7a57244ef0d8efe89a438715956b8336f23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Antihypertensive Agents - administration & dosage</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Glaucoma</topic><topic>Glaucoma, Open-Angle - physiopathology</topic><topic>Glaucoma, Open-Angle - surgery</topic><topic>Humans</topic><topic>Intraocular Pressure - physiology</topic><topic>Intraoperative Complications</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ophthalmology</topic><topic>Phacoemulsification</topic><topic>Postoperative Complications</topic><topic>Retrospective Studies</topic><topic>Tonometry, Ocular</topic><topic>Trabeculectomy - instrumentation</topic><topic>Trabeculectomy - methods</topic><topic>Visual Acuity - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakasato, Houmei</creatorcontrib><creatorcontrib>Uemoto, Riyo</creatorcontrib><creatorcontrib>Isozaki, Masaru</creatorcontrib><creatorcontrib>Meguro, Akira</creatorcontrib><creatorcontrib>Kawagoe, Tatsukata</creatorcontrib><creatorcontrib>Mizuki, Nobuhisa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakasato, Houmei</au><au>Uemoto, Riyo</au><au>Isozaki, Masaru</au><au>Meguro, Akira</au><au>Kawagoe, Tatsukata</au><au>Mizuki, Nobuhisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma</atitle><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle><stitle>Graefes Arch Clin Exp Ophthalmol</stitle><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>252</volume><issue>6</issue><spage>977</spage><epage>982</epage><pages>977-982</pages><issn>0721-832X</issn><eissn>1435-702X</eissn><abstract>Purpose
To describe a new technique to perform trabeculotomy
ab interno
on eyes with open-angle glaucoma (OAG).
Methods
This was a retrospective study. We inserted a 25-gauge forceps that is usually used for internal limiting membrane peeling into the anterior chamber, and grasped and pulled the inner wall of Schlemm’s canal away from the canal. The inner wall of Schlemm’s canal was stripped for about 100° to 120° in 26 eyes of 23 patients. The intraocular pressure (IOP) and number of glaucoma medications were recorded before, and 1 day, 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. The intra- and postoperative complications were recorded.
Results
The mean ± standard deviation of the preoperative IOP was 20.0 ± 6.8 mmHg with a range from 10 to 38 mmHg (
n
= 26). The IOP was significantly reduced (
P
< 0.05; paired
t
-tests) at 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 24, 19, 27, 30, and 33 months after the surgery. The mean preoperative number of glaucoma medications was significantly reduced (
P
< 0.001; paired
t
-tests) at 1 week, 2 weeks, and 1, 3, 6, 10, 12, 15, 17, 19, 24, 27, 30, and 33 months after the surgery. No vision-threatening complications were found in any of the cases, but there were blood clots in the anterior chamber postoperatively in 92.3 % of the cases.
Conclusions
Trabeculotomy
ab interno
for OAG is effective but with some minor complications. A larger number of patients with longer follow-up periods are needed to determine the long-term effectiveness of this procedure.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>24668387</pmid><doi>10.1007/s00417-014-2616-4</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0721-832X |
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| issn | 0721-832X 1435-702X |
| language | eng |
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| source | Springer Link |
| subjects | Aged Antihypertensive Agents - administration & dosage Female Follow-Up Studies Glaucoma Glaucoma, Open-Angle - physiopathology Glaucoma, Open-Angle - surgery Humans Intraocular Pressure - physiology Intraoperative Complications Male Medicine Medicine & Public Health Ophthalmology Phacoemulsification Postoperative Complications Retrospective Studies Tonometry, Ocular Trabeculectomy - instrumentation Trabeculectomy - methods Visual Acuity - physiology |
| title | Trabeculotomy ab interno with internal limiting membrane forceps for open-angle glaucoma |
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