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Effects of electrocardiogram gating on CT pulmonary angiography image quality

Introduction Pulmonary embolism (PE) is the third most common cause of death from cardiovascular disease. Computed‐tomographic pulmonary angiography (CTPA) is an accurate and safe test for diagnosing PE. The aim of this retrospective analysis was to evaluate the effects on image quality (IQ) of elec...

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Published in:Journal of medical imaging and radiation oncology 2014-06, Vol.58 (3), p.303-311
Main Authors: Ardley, Nicholas D, Lau, Ken K, Buchan, Kevin, Paul, Eldho, Troupis, John M
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Lau, Ken K
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description Introduction Pulmonary embolism (PE) is the third most common cause of death from cardiovascular disease. Computed‐tomographic pulmonary angiography (CTPA) is an accurate and safe test for diagnosing PE. The aim of this retrospective analysis was to evaluate the effects on image quality (IQ) of electrocardiogram (ECG) gating during CTPA. Methods Fifty consecutive patients presenting for CTPA were included in the study. A single acquisition was performed, resulting in two reconstructions: one at 75% of the R–R interval and the other without ECG influence. IQ evaluation was undertaken by two radiologists, focusing on respiratory and cardiac motion, image noise, low‐contrast resolution, vessel and lung clarity, contrast media opacification and artefacts. Various regions of the lungs and vasculature were evaluated, and IQ scores were statistically compared. Results For the ECG‐tagged reconstructions, IQ was noted to be better overall with regard to vessel clarity (P 
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Computed‐tomographic pulmonary angiography (CTPA) is an accurate and safe test for diagnosing PE. The aim of this retrospective analysis was to evaluate the effects on image quality (IQ) of electrocardiogram (ECG) gating during CTPA. Methods Fifty consecutive patients presenting for CTPA were included in the study. A single acquisition was performed, resulting in two reconstructions: one at 75% of the R–R interval and the other without ECG influence. IQ evaluation was undertaken by two radiologists, focusing on respiratory and cardiac motion, image noise, low‐contrast resolution, vessel and lung clarity, contrast media opacification and artefacts. Various regions of the lungs and vasculature were evaluated, and IQ scores were statistically compared. Results For the ECG‐tagged reconstructions, IQ was noted to be better overall with regard to vessel clarity (P &lt; 0.05) and cardiac motion (P &lt; 0.05), while lung clarity was better only in the left lower zone (P &lt; 0.05). IQ was better with regard to image noise (P &lt; 0.05) and low‐contrast resolution (P &lt; 0.05) in the non‐ECG‐tagged reconstructions. No statistical IQ difference between the two types of reconstruction was noted with regard to respiratory motion, contrast media opacification or presence of artefacts. Conclusion The two types of reconstruction provide complementary information for evaluating CTPA results.</description><identifier>ISSN: 1754-9477</identifier><identifier>EISSN: 1754-9485</identifier><identifier>DOI: 10.1111/1754-9485.12147</identifier><identifier>PMID: 24393120</identifier><language>eng</language><publisher>Australia: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Angiography - methods ; Cardiac-Gated Imaging Techniques - methods ; cardiopulmonary anatomy ; computed tomography ; Contrast agents ; Contrast Media - administration &amp; dosage ; ECG gating ; Electrocardiography ; Female ; Humans ; Injections, Intravenous ; Intelligence tests ; Iohexol - administration &amp; dosage ; Male ; Medical imaging ; Middle Aged ; Observer Variation ; Pulmonary Artery - diagnostic imaging ; pulmonary embolism ; Pulmonary Embolism - diagnostic imaging ; Radiographic Image Enhancement - methods ; Radiographic Image Interpretation, Computer-Assisted - methods ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, X-Ray Computed - methods ; vascular</subject><ispartof>Journal of medical imaging and radiation oncology, 2014-06, Vol.58 (3), p.303-311</ispartof><rights>2014 The Royal Australian and New Zealand College of Radiologists</rights><rights>2014 The Royal Australian and New Zealand College of Radiologists.</rights><rights>Copyright © 2014 Royal Australian and New Zealand College of Radiologists</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4117-8ebceb33c234a0d56d744e5aa5521021ab9eb27acca04cc3e3d4a37e1a0a79fa3</citedby><cites>FETCH-LOGICAL-c4117-8ebceb33c234a0d56d744e5aa5521021ab9eb27acca04cc3e3d4a37e1a0a79fa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24393120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ardley, Nicholas D</creatorcontrib><creatorcontrib>Lau, Ken K</creatorcontrib><creatorcontrib>Buchan, Kevin</creatorcontrib><creatorcontrib>Paul, Eldho</creatorcontrib><creatorcontrib>Troupis, John M</creatorcontrib><title>Effects of electrocardiogram gating on CT pulmonary angiography image quality</title><title>Journal of medical imaging and radiation oncology</title><addtitle>Journal of Medical Imaging and Radiation Oncology</addtitle><description>Introduction Pulmonary embolism (PE) is the third most common cause of death from cardiovascular disease. Computed‐tomographic pulmonary angiography (CTPA) is an accurate and safe test for diagnosing PE. The aim of this retrospective analysis was to evaluate the effects on image quality (IQ) of electrocardiogram (ECG) gating during CTPA. Methods Fifty consecutive patients presenting for CTPA were included in the study. A single acquisition was performed, resulting in two reconstructions: one at 75% of the R–R interval and the other without ECG influence. IQ evaluation was undertaken by two radiologists, focusing on respiratory and cardiac motion, image noise, low‐contrast resolution, vessel and lung clarity, contrast media opacification and artefacts. Various regions of the lungs and vasculature were evaluated, and IQ scores were statistically compared. Results For the ECG‐tagged reconstructions, IQ was noted to be better overall with regard to vessel clarity (P &lt; 0.05) and cardiac motion (P &lt; 0.05), while lung clarity was better only in the left lower zone (P &lt; 0.05). IQ was better with regard to image noise (P &lt; 0.05) and low‐contrast resolution (P &lt; 0.05) in the non‐ECG‐tagged reconstructions. No statistical IQ difference between the two types of reconstruction was noted with regard to respiratory motion, contrast media opacification or presence of artefacts. Conclusion The two types of reconstruction provide complementary information for evaluating CTPA results.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angiography - methods</subject><subject>Cardiac-Gated Imaging Techniques - methods</subject><subject>cardiopulmonary anatomy</subject><subject>computed tomography</subject><subject>Contrast agents</subject><subject>Contrast Media - administration &amp; dosage</subject><subject>ECG gating</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Intelligence tests</subject><subject>Iohexol - administration &amp; dosage</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Observer Variation</subject><subject>Pulmonary Artery - diagnostic imaging</subject><subject>pulmonary embolism</subject><subject>Pulmonary Embolism - diagnostic imaging</subject><subject>Radiographic Image Enhancement - methods</subject><subject>Radiographic Image Interpretation, Computer-Assisted - methods</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>vascular</subject><issn>1754-9477</issn><issn>1754-9485</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkE1P3DAURS1EBZSyZldZYsMm4OePcbIsI6BUUKQqiKX14jhpaBIPdiKaf98MA7NgU2_8ZJ179XwIOQZ2BvM5B61kkslUnQEHqXfIwfZldztrvU8-x_jE2AJAZntkn0uRCeDsgNxdVpWzQ6S-oq6dp-AthrLxdcCO1jg0fU19T5c5XY1t53sME8W-fgVWvyfadFg7-jxi2wzTF_Kpwja6o7f7kDxcXebL78nt_fXN8tttYiWATlJXWFcIYbmQyEq1KLWUTiEqxYFxwCJzBddoLTJprXCilCi0A2SoswrFITnd9K6Cfx5dHEzXROvaFnvnx2hACS5TLlU6oycf0Cc_hn7ebk2xVOtMw0ydbygbfIzBVWYV5p-FyQAza9Nm7dKsvZpX03Pi61vvWHSu3PLvamdAb4CXpnXT__rMj7ubX_fv1ckm2cTB_d0mMfwxCy20Mo8_r80yzyGX-sKk4h88J5eO</recordid><startdate>201406</startdate><enddate>201406</enddate><creator>Ardley, Nicholas D</creator><creator>Lau, Ken K</creator><creator>Buchan, Kevin</creator><creator>Paul, Eldho</creator><creator>Troupis, John M</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201406</creationdate><title>Effects of electrocardiogram gating on CT pulmonary angiography image quality</title><author>Ardley, Nicholas D ; Lau, Ken K ; Buchan, Kevin ; Paul, Eldho ; Troupis, John M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4117-8ebceb33c234a0d56d744e5aa5521021ab9eb27acca04cc3e3d4a37e1a0a79fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angiography - methods</topic><topic>Cardiac-Gated Imaging Techniques - methods</topic><topic>cardiopulmonary anatomy</topic><topic>computed tomography</topic><topic>Contrast agents</topic><topic>Contrast Media - administration &amp; dosage</topic><topic>ECG gating</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Intelligence tests</topic><topic>Iohexol - administration &amp; dosage</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Middle Aged</topic><topic>Observer Variation</topic><topic>Pulmonary Artery - diagnostic imaging</topic><topic>pulmonary embolism</topic><topic>Pulmonary Embolism - diagnostic imaging</topic><topic>Radiographic Image Enhancement - methods</topic><topic>Radiographic Image Interpretation, Computer-Assisted - methods</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>vascular</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ardley, Nicholas D</creatorcontrib><creatorcontrib>Lau, Ken K</creatorcontrib><creatorcontrib>Buchan, Kevin</creatorcontrib><creatorcontrib>Paul, Eldho</creatorcontrib><creatorcontrib>Troupis, John M</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medical imaging and radiation oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ardley, Nicholas D</au><au>Lau, Ken K</au><au>Buchan, Kevin</au><au>Paul, Eldho</au><au>Troupis, John M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of electrocardiogram gating on CT pulmonary angiography image quality</atitle><jtitle>Journal of medical imaging and radiation oncology</jtitle><addtitle>Journal of Medical Imaging and Radiation Oncology</addtitle><date>2014-06</date><risdate>2014</risdate><volume>58</volume><issue>3</issue><spage>303</spage><epage>311</epage><pages>303-311</pages><issn>1754-9477</issn><eissn>1754-9485</eissn><abstract>Introduction Pulmonary embolism (PE) is the third most common cause of death from cardiovascular disease. Computed‐tomographic pulmonary angiography (CTPA) is an accurate and safe test for diagnosing PE. The aim of this retrospective analysis was to evaluate the effects on image quality (IQ) of electrocardiogram (ECG) gating during CTPA. Methods Fifty consecutive patients presenting for CTPA were included in the study. A single acquisition was performed, resulting in two reconstructions: one at 75% of the R–R interval and the other without ECG influence. IQ evaluation was undertaken by two radiologists, focusing on respiratory and cardiac motion, image noise, low‐contrast resolution, vessel and lung clarity, contrast media opacification and artefacts. Various regions of the lungs and vasculature were evaluated, and IQ scores were statistically compared. Results For the ECG‐tagged reconstructions, IQ was noted to be better overall with regard to vessel clarity (P &lt; 0.05) and cardiac motion (P &lt; 0.05), while lung clarity was better only in the left lower zone (P &lt; 0.05). IQ was better with regard to image noise (P &lt; 0.05) and low‐contrast resolution (P &lt; 0.05) in the non‐ECG‐tagged reconstructions. No statistical IQ difference between the two types of reconstruction was noted with regard to respiratory motion, contrast media opacification or presence of artefacts. Conclusion The two types of reconstruction provide complementary information for evaluating CTPA results.</abstract><cop>Australia</cop><pub>Blackwell Publishing Ltd</pub><pmid>24393120</pmid><doi>10.1111/1754-9485.12147</doi><tpages>9</tpages></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Angiography - methods
Cardiac-Gated Imaging Techniques - methods
cardiopulmonary anatomy
computed tomography
Contrast agents
Contrast Media - administration & dosage
ECG gating
Electrocardiography
Female
Humans
Injections, Intravenous
Intelligence tests
Iohexol - administration & dosage
Male
Medical imaging
Middle Aged
Observer Variation
Pulmonary Artery - diagnostic imaging
pulmonary embolism
Pulmonary Embolism - diagnostic imaging
Radiographic Image Enhancement - methods
Radiographic Image Interpretation, Computer-Assisted - methods
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed - methods
vascular
title Effects of electrocardiogram gating on CT pulmonary angiography image quality
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