Diffuse Myocardial Uptake of (99m)Tc-HDP in Multiple Myeloma

Soft tissue uptake is a rare finding in bone scintigraphy, with an incidence of 2%. Although the mechanism has not yet been fully clarified, several causes have been reported for this unusual uptake pattern. This paper presents a case of diffuse myocardial accumulation of technetium-99m hydroxymethy...

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Bibliographic Details
Published in:Nuclear medicine and molecular imaging 2013-09, Vol.47 (3), p.208-211
Main Authors: Demirel, Koray, Sadic, Murat, Korkmaz, Meliha, Comak, Aylin, Atilgan, Hasan Ikbal, Koca, Gökhan
Format: Article
Language:English
Online Access:Get full text
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Summary:Soft tissue uptake is a rare finding in bone scintigraphy, with an incidence of 2%. Although the mechanism has not yet been fully clarified, several causes have been reported for this unusual uptake pattern. This paper presents a case of diffuse myocardial accumulation of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-HDP) without either solid/visceral organ or soft tissue with multiple myeloma (MM) in skeletal scintigraphy. A 93-year-old man with hypertension and chronic heart failure for 14 years underwent bone scanning due to a 2-month history of back pain within a 1-year period of MM. Three hours later, (99m)Tc-HDP late static images showed diffuse myocardial radiotracer accumulation and there were no other sites of abnormal soft tissue or visceral uptake. Myocardial accumulation had disappeared on 24-h delayed static images. This accumulation was thought to be related with AL-type amyloidosis associated with MM.
ISSN:1869-3474
DOI:10.1007/s13139-013-0209-5