Loading…
Device-Measured Physical Activity Versus Six-Minute Walk Test as a Predictor of Reverse Remodeling and Outcome After Cardiac Resynchronization Therapy for Heart Failure
Implanted devices can provide objective assessment of physical activity over prolonged periods. The purpose of this study was to investigate the prognostic value of device-measured physical activity data compared with a six-minute walk test (6MWT) in predicting clinical response to cardiac resynchro...
Saved in:
| Published in: | The American journal of cardiology 2014-05, Vol.113 (9), p.1523-1528 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383 |
| container_end_page | 1528 |
| container_issue | 9 |
| container_start_page | 1523 |
| container_title | The American journal of cardiology |
| container_volume | 113 |
| creator | Vegh, Eszter Maria, MD Kandala, Jagdesh, MD, MPH Orencole, Mary, ANP Upadhyay, Gaurav A., MD Sharma, Ajay, MD Miller, Alexandra, BA Merkely, Bela, MD, PhD, DSc Parks, Kimberly A., DO Singh, Jagmeet P., MD, DPhil |
| description | Implanted devices can provide objective assessment of physical activity over prolonged periods. The purpose of this study was to investigate the prognostic value of device-measured physical activity data compared with a six-minute walk test (6MWT) in predicting clinical response to cardiac resynchronization therapy (CRT). This was a single-center study in which patients who underwent CRT for standard indications were evaluated. Daily physical activity and 6MWT were evaluated postimplant at 1, 3, and 6 months. The primary end point was a composite of heart failure hospitalization, transplant, left ventricular (LV) assist device, and all-cause death at 3 years. Echocardiographic response, defined as a ≥10% improvement in LV ejection fraction (LVEF), at 6 months was the secondary end point. About 164 patients were included: average age was 67.3 ± 12.9 years, 77% were men, baseline LVEF was 25% ± 7%. Kaplan-Meier curves showed superior freedom from the composite end point in the highest tertile of both 6MWT and physical activity compared with the lowest tertile (41 vs 23 cases, respectively, p |
| doi_str_mv | 10.1016/j.amjcard.2014.01.430 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1534805448</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0002914914006328</els_id><sourcerecordid>3281532041</sourcerecordid><originalsourceid>FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383</originalsourceid><addsrcrecordid>eNqNksFu1DAQhiMEokvhEUCWuHBJsGPHSS6g1UIpUqtWdIGj5Thj1tsk3trOivBEPCaOdgGpFzhZlr75PeNvkuQ5wRnBhL_eZrLfKunaLMeEZZhkjOIHyYJUZZ2SmtCHyQJjnKc1YfVJ8sT7bbwSUvDHyUnOOCM154vk5zvYGwXpJUg_OmjR9WbyRskOLVUwexMm9AWcHz26Md_TSzOMAdBX2d2iNfiApEcSXcc6o4J1yGr0CfaRh3j2toXODN-QHFp0NQZle0BLHcChVezbSBUhPw1q4-xgfshg7IDWG3ByNyEd085BuoDOpOliZ0-TR1p2Hp4dz9Pk89n79eo8vbj68HG1vEhVwcqQSig4lYwTToHqomY5aFlUBOuqkVUJUDYlpnXdtFwTzWtoOC-atuJ5WeicVvQ0eXXI3Tl7N8YZRW-8gq6TA9jRC1JQVuGCsf9BCS_zmlc8oi_voVs7uiEOMlMVITxnZaSKA6Wc9d6BFjtneukmQbCYrYutOFoXs3WBiYjWY92LY_rY9ND-qfqtOQJvDwDEn9sbcMIrA4OK3hyoIFpr_vnEm3sJKrqdF-UWJvB_pxE-F1jczKs3bx5hGHOaV_QXJcjWPw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1518116247</pqid></control><display><type>article</type><title>Device-Measured Physical Activity Versus Six-Minute Walk Test as a Predictor of Reverse Remodeling and Outcome After Cardiac Resynchronization Therapy for Heart Failure</title><source>Elsevier</source><creator>Vegh, Eszter Maria, MD ; Kandala, Jagdesh, MD, MPH ; Orencole, Mary, ANP ; Upadhyay, Gaurav A., MD ; Sharma, Ajay, MD ; Miller, Alexandra, BA ; Merkely, Bela, MD, PhD, DSc ; Parks, Kimberly A., DO ; Singh, Jagmeet P., MD, DPhil</creator><creatorcontrib>Vegh, Eszter Maria, MD ; Kandala, Jagdesh, MD, MPH ; Orencole, Mary, ANP ; Upadhyay, Gaurav A., MD ; Sharma, Ajay, MD ; Miller, Alexandra, BA ; Merkely, Bela, MD, PhD, DSc ; Parks, Kimberly A., DO ; Singh, Jagmeet P., MD, DPhil</creatorcontrib><description>Implanted devices can provide objective assessment of physical activity over prolonged periods. The purpose of this study was to investigate the prognostic value of device-measured physical activity data compared with a six-minute walk test (6MWT) in predicting clinical response to cardiac resynchronization therapy (CRT). This was a single-center study in which patients who underwent CRT for standard indications were evaluated. Daily physical activity and 6MWT were evaluated postimplant at 1, 3, and 6 months. The primary end point was a composite of heart failure hospitalization, transplant, left ventricular (LV) assist device, and all-cause death at 3 years. Echocardiographic response, defined as a ≥10% improvement in LV ejection fraction (LVEF), at 6 months was the secondary end point. About 164 patients were included: average age was 67.3 ± 12.9 years, 77% were men, baseline LVEF was 25% ± 7%. Kaplan-Meier curves showed superior freedom from the composite end point in the highest tertile of both 6MWT and physical activity compared with the lowest tertile (41 vs 23 cases, respectively, p <0.001) for 6MWT and for activity (22 vs 7 cases, respectively, p = 0.001). In an adjusted multivariate model, independent predictors of improved clinical outcome included 1-month physical activity (hazard ratio 0.546, 95% confidence interval [CI] 0.361 to 0.824, p = 0.004) and 6MWT (hazard ratio 0.581, 95% CI 0.425 to 0.795, p = 0.001). An additional hour of higher activity at 1 month translated to a 1.38 times (95% CI 1.075 to 1.753, p = 0.011) higher likelihood of improved echocardiographic response. In conclusion, device-based measures of physical activity may be useful in predicting echocardiographic reverse remodeling and long-term clinical outcome in patients receiving CRT.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2014.01.430</identifier><identifier>PMID: 24641966</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Cardiac Resynchronization Therapy ; Cardiovascular ; Echocardiography ; Female ; Forecasting - methods ; Heart failure ; Heart Failure - physiopathology ; Heart Failure - therapy ; Hospitalization ; Humans ; Male ; Medical equipment ; Mortality ; Motor Activity ; Multivariate analysis ; Studies ; Transplants & implants ; Treatment Outcome ; Variables ; Ventricular Function, Left ; Ventricular Remodeling ; Walking</subject><ispartof>The American journal of cardiology, 2014-05, Vol.113 (9), p.1523-1528</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited May 1, 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383</citedby><cites>FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24641966$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vegh, Eszter Maria, MD</creatorcontrib><creatorcontrib>Kandala, Jagdesh, MD, MPH</creatorcontrib><creatorcontrib>Orencole, Mary, ANP</creatorcontrib><creatorcontrib>Upadhyay, Gaurav A., MD</creatorcontrib><creatorcontrib>Sharma, Ajay, MD</creatorcontrib><creatorcontrib>Miller, Alexandra, BA</creatorcontrib><creatorcontrib>Merkely, Bela, MD, PhD, DSc</creatorcontrib><creatorcontrib>Parks, Kimberly A., DO</creatorcontrib><creatorcontrib>Singh, Jagmeet P., MD, DPhil</creatorcontrib><title>Device-Measured Physical Activity Versus Six-Minute Walk Test as a Predictor of Reverse Remodeling and Outcome After Cardiac Resynchronization Therapy for Heart Failure</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Implanted devices can provide objective assessment of physical activity over prolonged periods. The purpose of this study was to investigate the prognostic value of device-measured physical activity data compared with a six-minute walk test (6MWT) in predicting clinical response to cardiac resynchronization therapy (CRT). This was a single-center study in which patients who underwent CRT for standard indications were evaluated. Daily physical activity and 6MWT were evaluated postimplant at 1, 3, and 6 months. The primary end point was a composite of heart failure hospitalization, transplant, left ventricular (LV) assist device, and all-cause death at 3 years. Echocardiographic response, defined as a ≥10% improvement in LV ejection fraction (LVEF), at 6 months was the secondary end point. About 164 patients were included: average age was 67.3 ± 12.9 years, 77% were men, baseline LVEF was 25% ± 7%. Kaplan-Meier curves showed superior freedom from the composite end point in the highest tertile of both 6MWT and physical activity compared with the lowest tertile (41 vs 23 cases, respectively, p <0.001) for 6MWT and for activity (22 vs 7 cases, respectively, p = 0.001). In an adjusted multivariate model, independent predictors of improved clinical outcome included 1-month physical activity (hazard ratio 0.546, 95% confidence interval [CI] 0.361 to 0.824, p = 0.004) and 6MWT (hazard ratio 0.581, 95% CI 0.425 to 0.795, p = 0.001). An additional hour of higher activity at 1 month translated to a 1.38 times (95% CI 1.075 to 1.753, p = 0.011) higher likelihood of improved echocardiographic response. In conclusion, device-based measures of physical activity may be useful in predicting echocardiographic reverse remodeling and long-term clinical outcome in patients receiving CRT.</description><subject>Aged</subject><subject>Cardiac Resynchronization Therapy</subject><subject>Cardiovascular</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Forecasting - methods</subject><subject>Heart failure</subject><subject>Heart Failure - physiopathology</subject><subject>Heart Failure - therapy</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Male</subject><subject>Medical equipment</subject><subject>Mortality</subject><subject>Motor Activity</subject><subject>Multivariate analysis</subject><subject>Studies</subject><subject>Transplants & implants</subject><subject>Treatment Outcome</subject><subject>Variables</subject><subject>Ventricular Function, Left</subject><subject>Ventricular Remodeling</subject><subject>Walking</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqNksFu1DAQhiMEokvhEUCWuHBJsGPHSS6g1UIpUqtWdIGj5Thj1tsk3trOivBEPCaOdgGpFzhZlr75PeNvkuQ5wRnBhL_eZrLfKunaLMeEZZhkjOIHyYJUZZ2SmtCHyQJjnKc1YfVJ8sT7bbwSUvDHyUnOOCM154vk5zvYGwXpJUg_OmjR9WbyRskOLVUwexMm9AWcHz26Md_TSzOMAdBX2d2iNfiApEcSXcc6o4J1yGr0CfaRh3j2toXODN-QHFp0NQZle0BLHcChVezbSBUhPw1q4-xgfshg7IDWG3ByNyEd085BuoDOpOliZ0-TR1p2Hp4dz9Pk89n79eo8vbj68HG1vEhVwcqQSig4lYwTToHqomY5aFlUBOuqkVUJUDYlpnXdtFwTzWtoOC-atuJ5WeicVvQ0eXXI3Tl7N8YZRW-8gq6TA9jRC1JQVuGCsf9BCS_zmlc8oi_voVs7uiEOMlMVITxnZaSKA6Wc9d6BFjtneukmQbCYrYutOFoXs3WBiYjWY92LY_rY9ND-qfqtOQJvDwDEn9sbcMIrA4OK3hyoIFpr_vnEm3sJKrqdF-UWJvB_pxE-F1jczKs3bx5hGHOaV_QXJcjWPw</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Vegh, Eszter Maria, MD</creator><creator>Kandala, Jagdesh, MD, MPH</creator><creator>Orencole, Mary, ANP</creator><creator>Upadhyay, Gaurav A., MD</creator><creator>Sharma, Ajay, MD</creator><creator>Miller, Alexandra, BA</creator><creator>Merkely, Bela, MD, PhD, DSc</creator><creator>Parks, Kimberly A., DO</creator><creator>Singh, Jagmeet P., MD, DPhil</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20140501</creationdate><title>Device-Measured Physical Activity Versus Six-Minute Walk Test as a Predictor of Reverse Remodeling and Outcome After Cardiac Resynchronization Therapy for Heart Failure</title><author>Vegh, Eszter Maria, MD ; Kandala, Jagdesh, MD, MPH ; Orencole, Mary, ANP ; Upadhyay, Gaurav A., MD ; Sharma, Ajay, MD ; Miller, Alexandra, BA ; Merkely, Bela, MD, PhD, DSc ; Parks, Kimberly A., DO ; Singh, Jagmeet P., MD, DPhil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Cardiac Resynchronization Therapy</topic><topic>Cardiovascular</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Forecasting - methods</topic><topic>Heart failure</topic><topic>Heart Failure - physiopathology</topic><topic>Heart Failure - therapy</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Male</topic><topic>Medical equipment</topic><topic>Mortality</topic><topic>Motor Activity</topic><topic>Multivariate analysis</topic><topic>Studies</topic><topic>Transplants & implants</topic><topic>Treatment Outcome</topic><topic>Variables</topic><topic>Ventricular Function, Left</topic><topic>Ventricular Remodeling</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vegh, Eszter Maria, MD</creatorcontrib><creatorcontrib>Kandala, Jagdesh, MD, MPH</creatorcontrib><creatorcontrib>Orencole, Mary, ANP</creatorcontrib><creatorcontrib>Upadhyay, Gaurav A., MD</creatorcontrib><creatorcontrib>Sharma, Ajay, MD</creatorcontrib><creatorcontrib>Miller, Alexandra, BA</creatorcontrib><creatorcontrib>Merkely, Bela, MD, PhD, DSc</creatorcontrib><creatorcontrib>Parks, Kimberly A., DO</creatorcontrib><creatorcontrib>Singh, Jagmeet P., MD, DPhil</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest research library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vegh, Eszter Maria, MD</au><au>Kandala, Jagdesh, MD, MPH</au><au>Orencole, Mary, ANP</au><au>Upadhyay, Gaurav A., MD</au><au>Sharma, Ajay, MD</au><au>Miller, Alexandra, BA</au><au>Merkely, Bela, MD, PhD, DSc</au><au>Parks, Kimberly A., DO</au><au>Singh, Jagmeet P., MD, DPhil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Device-Measured Physical Activity Versus Six-Minute Walk Test as a Predictor of Reverse Remodeling and Outcome After Cardiac Resynchronization Therapy for Heart Failure</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>113</volume><issue>9</issue><spage>1523</spage><epage>1528</epage><pages>1523-1528</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Implanted devices can provide objective assessment of physical activity over prolonged periods. The purpose of this study was to investigate the prognostic value of device-measured physical activity data compared with a six-minute walk test (6MWT) in predicting clinical response to cardiac resynchronization therapy (CRT). This was a single-center study in which patients who underwent CRT for standard indications were evaluated. Daily physical activity and 6MWT were evaluated postimplant at 1, 3, and 6 months. The primary end point was a composite of heart failure hospitalization, transplant, left ventricular (LV) assist device, and all-cause death at 3 years. Echocardiographic response, defined as a ≥10% improvement in LV ejection fraction (LVEF), at 6 months was the secondary end point. About 164 patients were included: average age was 67.3 ± 12.9 years, 77% were men, baseline LVEF was 25% ± 7%. Kaplan-Meier curves showed superior freedom from the composite end point in the highest tertile of both 6MWT and physical activity compared with the lowest tertile (41 vs 23 cases, respectively, p <0.001) for 6MWT and for activity (22 vs 7 cases, respectively, p = 0.001). In an adjusted multivariate model, independent predictors of improved clinical outcome included 1-month physical activity (hazard ratio 0.546, 95% confidence interval [CI] 0.361 to 0.824, p = 0.004) and 6MWT (hazard ratio 0.581, 95% CI 0.425 to 0.795, p = 0.001). An additional hour of higher activity at 1 month translated to a 1.38 times (95% CI 1.075 to 1.753, p = 0.011) higher likelihood of improved echocardiographic response. In conclusion, device-based measures of physical activity may be useful in predicting echocardiographic reverse remodeling and long-term clinical outcome in patients receiving CRT.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24641966</pmid><doi>10.1016/j.amjcard.2014.01.430</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 2014-05, Vol.113 (9), p.1523-1528 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1534805448 |
| source | Elsevier |
| subjects | Aged Cardiac Resynchronization Therapy Cardiovascular Echocardiography Female Forecasting - methods Heart failure Heart Failure - physiopathology Heart Failure - therapy Hospitalization Humans Male Medical equipment Mortality Motor Activity Multivariate analysis Studies Transplants & implants Treatment Outcome Variables Ventricular Function, Left Ventricular Remodeling Walking |
| title | Device-Measured Physical Activity Versus Six-Minute Walk Test as a Predictor of Reverse Remodeling and Outcome After Cardiac Resynchronization Therapy for Heart Failure |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T08%3A02%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Device-Measured%20Physical%20Activity%20Versus%20Six-Minute%20Walk%20Test%20as%20a%20Predictor%20of%20Reverse%20Remodeling%20and%20Outcome%20After%20Cardiac%20Resynchronization%20Therapy%20for%20Heart%20Failure&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Vegh,%20Eszter%20Maria,%20MD&rft.date=2014-05-01&rft.volume=113&rft.issue=9&rft.spage=1523&rft.epage=1528&rft.pages=1523-1528&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2014.01.430&rft_dat=%3Cproquest_cross%3E3281532041%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c547t-ae563a46163e3f5942efa5810f8ba87ee7b70399bd6f1f69eb665bd86275f2383%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1518116247&rft_id=info:pmid/24641966&rfr_iscdi=true |