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Anticancer activity of 4-aminoquinoline-triazine based molecular hybrids

In this study the potential for anticancer activity of 4-aminoquinoline-triazine based hybrids has been investigated on 60 human cancer cell lines (NCI 60). The representative compounds show activity on a range of cell lines and apoptosis as the mode of growth inhibition.

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Bibliographic Details
Published in:RSC advances 2014, Vol.4 (14), p.7062-7067
Main Authors: Manohar, Sunny, Pepe, Antonella, VĂ©lez Gerena, Christian E., Zayas, Beatriz, Malhotra, Sanjay V., Rawat, Diwan S.
Format: Article
Language:English
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Summary:In this study the potential for anticancer activity of 4-aminoquinoline-triazine based hybrids has been investigated on 60 human cancer cell lines (NCI 60). The representative compounds show activity on a range of cell lines and apoptosis as the mode of growth inhibition.
ISSN:2046-2069
2046-2069
DOI:10.1039/c3ra45333b